Angiotensin-converting enzyme 2 expression and severity of SARS-CoV-2 infection

S Alabsi, A Dhole, S Hozayen, SA Chapman - Microorganisms, 2023 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2), first discovered in 2000, serves as an important
counterregulatory enzyme to the angiotensin II-mediated vasoconstrictive, pro-inflammatory …

Treating COVID-19: targeting the host response, not the virus

DS Fedson - Life, 2023 - mdpi.com
In low-and middle-income countries (LMICs), inexpensive generic drugs like statins, ACE
inhibitors, and ARBs, especially if used in combination, might be the only practical way to …

[HTML][HTML] Association of cardiovascular medications with adverse outcomes in a matched analysis of a national cohort of patients with COVID-19

LK Wang, YF Kuo, J Westra, MA Raji… - American journal of …, 2023 - Elsevier
Background The use of statins, angiotensin-converting enzyme inhibitors
(ACEIs)/angiotensin II receptor blockers (ARBs), and anticoagulants may be associated with …

Doxycycline's Potential Role in Reducing Thrombosis and Mortality in Critically Ill Patients With COVID-19: A Multicenter Cohort Study

K Al Sulaiman, O Aljuhani… - Clinical and Applied …, 2023 - journals.sagepub.com
Doxycycline has revealed potential effects in animal studies to prevent thrombosis and
reduce mortality. However, less is known about its antithrombotic role in patients with COVID …

[HTML][HTML] Statin use and clinical outcomes in hospitalized COVID-19 patients: A retrospective analysis in Riyadh, Saudi Arabia

KS Alshaalan, RF Alkahtani, RF Althobaiti… - Saudi Medical …, 2024 - ncbi.nlm.nih.gov
Objectives: To investigate the relationship between statin use and coronavirus disease-19
(COVID-19) severity. Methods: This was a retrospective study of adult patients with …

Statin Therapy to Improve Outcome of COVID-19 Patients: Useful or Not Useful?

B Mégarbane - Journal of Personalized Medicine, 2022 - mdpi.com
About one year ago, the journal published a large population-based cohort study from South
Korea investigating the potential benefits associated with statins at preventing severe acute …