While lung cancer has been the leading cause of cancer-related deaths for many years in
the United States, incidence and mortality statistics–among other measures–vary widely …

Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

The European Prospective Investigation into Cancer and Nutrition (EPIC) is a multicentre
prospective study conducted in 23 centres in 10 European countries. Here we review the …

The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), serves as a co-factor in more
than 150 enzymatic reactions. Plasma PLP has consistently been shown to be low in …

Measures of B6 status are categorized as direct biomarkers and as functional biomarkers.
Direct biomarkers measure B6 vitamers in plasma/serum, urine and erythrocytes, and …

Context Prenatal folic acid supplements reduce the risk of neural tube defects and may have
beneficial effects on other aspects of neurodevelopment. Objective To examine associations …

Dietary and other environmental factors induce epigenetic alterations which may have
important consequences for cancer development. This chapter summarizes current …

Riboflavin is a water-soluble vitamin, which was initially isolated from milk. There are two
coenzyme forms of riboflavin, flavin mononucleotide and flavin adenine dinucleotide, in …

Although epidemiological studies support the role of environment in a wide range of human
cancers, the precise mechanisms by which environmental exposures promote cancer …

Lung cancer is the most common form of cancer death worldwide. Although reduction of
tobacco consumption remains the most appropriate strategy to reduce lung-cancer burden …