Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus

T Nuutinen - European journal of medicinal chemistry, 2018 - Elsevier
Cannabaceae plants Cannabis sativa L. and Humulus lupulus L. are rich in terpenes–both
are typically comprised of terpenes as up to 3–5% of the dry-mass of the female …

Essential oils and isolated terpenes in nanosystems designed for topical administration: A review

SP de Matos, HF Teixeira, ÁAN De Lima… - Biomolecules, 2019 - mdpi.com
Essential oils are natural products with a complex composition. Terpenes are the most
common class of chemical compounds present in essential oils. Terpenes and the essential …

Health benefits, pharmacological effects, molecular mechanisms, and therapeutic potential of α-bisabolol

LB Eddin, NK Jha, SN Goyal, YO Agrawal… - Nutrients, 2022 - mdpi.com
α-Bisabolol is one of the important monocyclic sesquiterpenes, derived naturally from
essential oils of many edible and ornamental plants. It was first obtained from Matricaria …

Dacarbazine nanoparticle topical delivery system for the treatment of melanoma

A Hafeez, I Kazmi - Scientific reports, 2017 - nature.com
Dacarbazine (DZ) is poorly soluble in water with the short half-life in blood circulation, low
rate of response with the toxic effect which ultimately limits its utilization of the treatment of …

Adult Zebrafish (Danio rerio) As a Model for the Study of Corneal Antinociceptive Compounds

FEA Magalhães, FLA Batista, LMG Lima, IA Abrante… - Zebrafish, 2018 - liebertpub.com
Zebrafish is an excellent model that can be utilized as an adjunct to current rodent models
for studies of eye diseases because the anatomy and ultrastructural characterization of its …

Biologically active compounds from Lamiaceae family: Central nervous system effects

A Abdelhalim, J Hanrahan - Studies in natural products chemistry, 2021 - Elsevier
Lamiaceae, also known as the mint family, is a family of plants comprising about 245 genera
and 7886 species distributed all over the world. Plants of this family are widely used in folk …

Antinociceptive activity of chemical components of essential oils that involves docking studies: a review

DB Assis, HC Aragão Neto, DV da Fonsêca… - Frontiers in …, 2020 - frontiersin.org
Introduction Pain is considered an unpleasant sensory and emotional experience, being
considered as one of the most important causes of human suffering. Computational …

Natural active ingredients and TRPV1 modulation: focus on key chemical moieties involved in ligand–target interaction

C Andrei, A Zanfirescu, GM Nițulescu, OT Olaru… - Plants, 2023 - mdpi.com
Diseases such as cancer, neurological pathologies and chronic pain represent currently
unmet needs. The existing pharmacotherapeutic options available for treating these …

Are structurally modified galactomannan derivatives biologically active?

MS Geronço, IF da Silveira Ramos, EC da Silva Filho… - Polysaccharides, 2021 - mdpi.com
Galactomannans are versatile macromolecules with broad industrial potential. The influence
of changes in the chemical structures and respective bioactivities of these polysaccharides …

[HTML][HTML] (−)-α-Bisabolol reduces nociception and trigeminal central sensitisation in acute orofacial neuropathic pain induced by infraorbital nerve injury

LT Melo, V Panchalingam, P Cherkas, AR Campos… - Life sciences, 2019 - Elsevier
Neuropathic orofacial pain conditions represent a challenge to diagnose and treat. Natural
substances are promising therapeutic options for the control of pain. Aims This study aimed …