Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Serpin-loaded extracellular vesicles promote tissue repair in a mouse model of impaired wound healing

DJ Park, E Duggan, K Ho, RA Dorschner… - Journal of …, 2022 - Springer
Chronic metabolic diseases such as diabetes are characterized by delayed wound healing
and a dysregulation of the inflammatory phase of wound repair. Our study focuses on …

Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds

R Sun, C Liu, J Liu, S Yin, R Song, J Ma, G Cao… - Scientific Reports, 2023 - nature.com
Naringenin is a citrus flavonoid with various biological functions and a potential therapeutic
agent for skin diseases, such as UV radiation and atopic dermatitis. The present study …

[HTML][HTML] FADD-and RIPK3-Mediated Cell Death Ensures Clearance of Ly6Chigh Wound Macrophages from Damaged Tissue

L Injarabian, S Willenborg, D Welcker, DE Sanin… - Journal of Investigative …, 2024 - Elsevier
Cells of the monocyte/macrophage lineage are an integral component of the body's innate
ability to restore tissue function after injury. In parallel to mounting an inflammatory …

Orphan GPR26 counteracts early phases of hyperglycemia-mediated monocyte activation and is suppressed in diabetic patients

ZA Kichi, L Natarelli, S Sadeghian, MA Boroumand… - Biomedicines, 2022 - mdpi.com
Diabetes is the ninth leading cause of death, with an estimated 1.5 million deaths worldwide.
Type 2 diabetes (T2D) results from the body's ineffective use of insulin and is largely the …

FADD-and RIPK3-mediated cell death ensures timely clearance of wound macrophages and promotes wound healing

L Injarabian, S Willenborg, D Welcker, M Pasparakis… - bioRxiv, 2023 - biorxiv.org
Cells of the monocyte/macrophage lineage are an integral component of the body's innate
ability to restore tissue function after injury. In parallel to mounting an inflammatory …