Understanding cancer and the anticancer activities of naphthoquinones–a review

KW Wellington - RSC advances, 2015 - pubs.rsc.org
The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

The value of pyrans as anticancer scaffolds in medicinal chemistry

D Kumar, P Sharma, H Singh, K Nepali, GK Gupta… - RSC …, 2017 - pubs.rsc.org
Pyran is an oxygen-containing heterocyclic moiety, which exhibits an array of
pharmacological properties. Pyran is also one of the important structural subunits found …

Perspectives for natural product based agents derived from industrial plants in textile applications–a review

M Shahid, F Mohammad - Journal of cleaner production, 2013 - Elsevier
With the consumer's enhanced awareness of eco-safety, there has been an increasing
tendency towards the use of sustainable and environmentally friendly materials. In recent …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Biosynthesis and molecular actions of specialized 1, 4-naphthoquinone natural products produced by horticultural plants

JR Widhalm, D Rhodes - Horticulture Research, 2016 - academic.oup.com
Abstract The 1, 4-naphthoquinones (1, 4-NQs) are a diverse group of natural products found
in every kingdom of life. Plants, including many horticultural species, collectively synthesize …

Monodentately-coordinated bioactive moieties in multimodal half-sandwich organoruthenium anticancer agents

TR Steel, F Walsh, A Wieczorek-Błauż, M Hanif… - Coordination chemistry …, 2021 - Elsevier
Metallodrugs have a central role in the treatment and diagnosis of diseases. To overcome
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …

Comprehensive review on various strategies for antimalarial drug discovery

M Mishra, VK Mishra, V Kashaw, AK Iyer… - European journal of …, 2017 - Elsevier
The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …

[HTML][HTML] The trypanocidal activity of naphthoquinones: a review

AV Pinto, SL de Castro - Molecules, 2009 - ncbi.nlm.nih.gov
Naphthoquinones are compounds present in several families of higher plants. Their
molecular structures confer redox properties, and they are involved in multiple biological …

Updates on the clinical evidenced herb‐warfarin interactions

B Ge, Z Zhang, Z Zuo - Evidence‐Based Complementary and …, 2014 - Wiley Online Library
Increasing and inadvertent use of herbs makes herb‐drug interactions a focus of research.
Concomitant use of warfarin, a highly efficacious oral anticoagulant, and herbs causes major …

Recent advances of human dihydroorotate dehydrogenase inhibitors for cancer therapy: Current development and future perspectives

L Zhang, J Zhang, J Wang, C Ren, P Tang… - European journal of …, 2022 - Elsevier
Human dihydroorotate dehydrogenase (hDHODH) is a flavin-dependent enzyme catalyzing
the fourth step of pyrimidine de novo biosynthesis. Since aberrant pyrimidine metabolism is …