The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …
Brain modularity: a biomarker of intervention-related plasticity
CL Gallen, M D'Esposito - Trends in cognitive sciences, 2019 - cell.com
Interventions using methods such as cognitive training and aerobic exercise have shown
potential to enhance cognitive abilities. However, there is often pronounced individual …
potential to enhance cognitive abilities. However, there is often pronounced individual …
The effect of aging on resting state connectivity of predefined networks in the brain
Recent studies have found a deleterious effect of age on a wide variety of measures of
functional connectivity, and some hints at a relationship between connectivity at rest and …
functional connectivity, and some hints at a relationship between connectivity at rest and …
Age-related neural dedifferentiation and cognition
This review focuses on possible contributions of neural dedifferentiation to age-related
cognitive decline. Neural dedifferentiation is held to reflect a breakdown in the functional …
cognitive decline. Neural dedifferentiation is held to reflect a breakdown in the functional …
[HTML][HTML] Functional dedifferentiation of associative resting state networks in older adults–a longitudinal study
Healthy aging is associated with weaker functional connectivity within resting state brain
networks and stronger functional interaction between these networks. This phenomenon has …
networks and stronger functional interaction between these networks. This phenomenon has …
Leveraging technology to personalize cognitive enhancement methods in aging
As population aging advances at an increasing rate, efforts to help people maintain or
improve cognitive function late in life are critical. Although some studies have shown …
improve cognitive function late in life are critical. Although some studies have shown …
Longitudinal functional brain network reconfiguration in healthy aging
B Malagurski, F Liem, J Oschwald… - Human Brain …, 2020 - Wiley Online Library
Healthy aging is associated with changes in cognitive performance and functional brain
organization. In fact, cross‐sectional studies imply lower modularity and significant …
organization. In fact, cross‐sectional studies imply lower modularity and significant …
Brain network modularity predicts improvements in cognitive and scholastic performance in children involved in a physical activity intervention
L Chaddock-Heyman, TB Weng, C Kienzler… - Frontiers in Human …, 2020 - frontiersin.org
Introduction: Brain network modularity is a principle that quantifies the degree to which
functional brain networks are divided into subnetworks. Higher modularity reflects a greater …
functional brain networks are divided into subnetworks. Higher modularity reflects a greater …
Alzheimer's pathology is associated with dedifferentiation of intrinsic functional memory networks in aging
In presymptomatic Alzheimer's disease (AD), beta-amyloid plaques (Aβ) and tau tangles
accumulate in distinct spatiotemporal patterns within the brain, tracking closely with episodic …
accumulate in distinct spatiotemporal patterns within the brain, tracking closely with episodic …
High-definition transcranial direct current stimulation enhances network segregation during spatial navigation in mild cognitive impairment
AD Iordan, S Ryan, T Tyszkowski, SJ Peltier… - Cerebral …, 2022 - academic.oup.com
Spatial navigation is essential for everyday life and relies on complex network-level
interactions. Recent evidence suggests that transcranial direct current stimulation (tDCS) …
interactions. Recent evidence suggests that transcranial direct current stimulation (tDCS) …