Mitochondrial energetic adaptations encompass a plethora of conserved processes that
maintain cell and organismal fitness and survival in the changing environment by adjusting …

Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …

Stress granules (SGs) are membraneless cell compartments formed in response to different
stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other …

Previously, we identified ISRIB as a potent inhibitor of the integrated stress response (ISR)
and showed that ISRIB makes cells resistant to the effects of eIF2α phosphorylation and …

RNA binding proteins that act at the post-transcriptional level display a richness of
mechanisms to modulate the transcriptional output and respond to changing cellular …

The control of translation and mRNA degradation is important in the regulation of eukaryotic
gene expression. In general, translation and steps in the major pathway of mRNA decay are …

Stress granule (SG) assembly is a conserved cellular strategy to minimize stress-related
damage and promote cell survival. Beyond their fundamental role in the stress response …

Messenger ribonucleoprotein (mRNP) granules are dynamic, self-assembling structures that
harbor non-translating mRNAs bound by various proteins that regulate mRNA translation …

The stress response in eukaryotic cells often inhibits translation initiation and leads to the
formation of cytoplasmic RNA-protein complexes referred to as stress granules. Stress …

All cells possess an internal stress response to cope with environmental and
pathophysiological challenges. Upon stress, cells reprogram their molecular functions to …