[HTML][HTML] SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

[HTML][HTML] Innate immunity: the first line of defense against SARS-CoV-2

MS Diamond, TD Kanneganti - Nature immunology, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

[HTML][HTML] Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

[HTML][HTML] SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection

R Karki, SJ Lee, R Mall, N Pandian, Y Wang… - Science …, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 …

Y Zheng, MW Zhuang, L Han, J Zhang… - Signal transduction and …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected …

The physiological functions of human peroxisomes

RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

SARS-CoV-2 biology and host interactions

S Steiner, A Kratzel, GT Barut, RM Lang… - Nature Reviews …, 2024 - nature.com
The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …

[HTML][HTML] IgG4 antibodies induced by repeated vaccination may generate immune tolerance to the SARS-CoV-2 spike protein

VN Uversky, EM Redwan, W Makis, A Rubio-Casillas - Vaccines, 2023 - mdpi.com
Less than a year after the global emergence of the coronavirus SARS-CoV-2, a novel
vaccine platform based on mRNA technology was introduced to the market. Globally, around …

[HTML][HTML] Roles and functions of SARS-CoV-2 proteins in host immune evasion

F Rashid, Z Xie, M Suleman, A Shah, S Khan… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …