Cellular mechanisms of aortic aneurysm formation

RA Quintana, WR Taylor - Circulation Research, 2019 - Am Heart Assoc
Aortic aneurysms are a common vascular disease in Western populations that can involve
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …

Basic components of connective tissues and extracellular matrix: elastin, fibrillin, fibulins, fibrinogen, fibronectin, laminin, tenascins and thrombospondins

J Halper, M Kjaer - Progress in heritable soft connective tissue diseases, 2014 - Springer
Collagens are the most abundant components of the extracellular matrix and many types of
soft tissues. Elastin is another major component of certain soft tissues, such as arterial walls …

[PDF][PDF] 2014 ESC guidelines on the diagnosis and treatment of aortic diseases

R Erbel, V Aboyans, C Boileau… - Kardiologia Polska …, 2014 - journals.viamedica.pl
Poziom B Dane pochodzące z jednej randomizowanej próby klinicznej lub dużych badań
nierandomizowanych Poziom C Uzgodniona opinia ekspertów i/lub dane pochodzące z …

[图书][B] Rutherford's vascular surgery e-book

JL Cronenwett, KW Johnston - 2014 - books.google.com
Published in association with the Society for Vascular Surgery, Rutherford's Vascular
Surgery presents state-of-the-art updates on all aspects of vascular health care. Extensively …

[HTML][HTML] The Human Phenotype Ontology: a tool for annotating and analyzing human hereditary disease

PN Robinson, S Köhler, S Bauer, D Seelow… - The American Journal of …, 2008 - cell.com
There are many thousands of hereditary diseases in humans, each of which has a specific
combination of phenotypic features, but computational analysis of phenotypic data has been …

[HTML][HTML] TGF-β superfamily signaling in embryonic development and homeostasis

MY Wu, CS Hill - Developmental cell, 2009 - cell.com
TGF-β superfamily signaling pathways emerged with the evolution of multicellular animals,
suggesting that these pathways contribute to the increased diversity and complexity required …

[图书][B] Robbins y Cotran. Patología estructural y funcional

V Kumar, AK Abbas, JC Aster - 2021 - books.google.com
Nueva edición del tratado de referencia en la disciplina que expone los fundamentos de la
anatomía patológica con un formato atractivo y de fácil consulta, que garantiza el acceso a …

FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders

LY Sakai, DR Keene, M Renard, J De Backer - Gene, 2016 - Elsevier
FBN1 encodes the gene for fibrillin-1, a structural macromolecule that polymerizes into
microfibrils. Fibrillin microfibrils are morphologically distinctive fibrils, present in all …

[HTML][HTML] TGF-β signaling in vascular biology and dysfunction

MJ Goumans, Z Liu, P Ten Dijke - Cell research, 2009 - nature.com
Transforming growth factor (TGF)-β family members are multifunctional cytokines that elicit
their effects on cells, including endothelial and mural cells, via specific type I and type II …

Extracellular control of TGFβ signalling in vascular development and disease

P Ten Dijke, HM Arthur - Nature reviews Molecular cell biology, 2007 - nature.com
The intracellular mechanism of transforming growth factor-β (TGFβ) signalling via kinase
receptors and SMAD effectors is firmly established, but recent studies of human …