Achieving abstinence from drugs is a long journey and can be particularly challenging in the
case of methamphetamine, which has a higher relapse rate than other drugs. Therefore, real …

The habenula (Hb) is central to adaptive reward-and aversion-driven behaviors, comprising
a hub for higher-order processing networks involving the prefrontal cortex (PFC). Despite an …

Substance use disorders (SUD) is defined as a chronic, relapsing disorder characterized by
compulsive drug seeking and use despite adverse consequences, which is frequently …

Background Patients with stimulant use disorder experience high rates of relapse. While
neurobehavioral mechanisms involved in initiating drug use have been studied extensively …

The insular cortex (IC) has been linked to the processing of interoceptive and exteroceptive
signals associated with addictive behavior. However, whether the IC modulates the …

Background Progress have been made in brain function recovery after long-term abstinence
in person with heroin addiction (PHA). However, less is known about whether the nucleus …

Background Individual differences have been detected in individuals with opioid use
disorders (OUD) in rehabilitation following protracted abstinence. Recent studies suggested …

Are decisions associated with risk and uncertainty made differently across the life span? In
this preregistered study we performed a multiverse analysis to exhaustively examine age …

Addiction is characterized by a persistent cycle of drug seeking and taking as well as high
relapse rate. Neuroimaging technology offers an opportunity to elucidate the brain …

Functional responses in the Nucleus Accumbens (NAcc) to risk-and reward-related cues can
predict real-life risk-taking behavior. Since NAcc activity is driven by neurotransmission from …