[HTML][HTML] Zinc in human health and infectious diseases

M Maywald, L Rink - Biomolecules, 2022 - mdpi.com
During the last few decades, the micronutrient zinc has proven to be an important metal ion
for a well-functioning immune system, and thus also for a suitable immune defense …

[HTML][HTML] Mechanism of sorafenib resistance associated with ferroptosis in HCC

L Guo, C Hu, M Yao, G Han - Frontiers in pharmacology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most familiar primary hepatic malignancy with a poor
prognosis. The incidence of HCC and the associated deaths have risen in recent decades …

[HTML][HTML] Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver

T Hautz, S Salcher, M Fodor, G Sturm, S Ebner… - Nature …, 2023 - nature.com
Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation
technique. Developing an understanding for the donor organ immune cell composition and …

[HTML][HTML] Lactation-associated macrophages exist in murine mammary tissue and human milk

D Cansever, E Petrova, S Krishnarajah, C Mussak… - Nature …, 2023 - nature.com
Macrophages are involved in immune defense, organogenesis and tissue homeostasis.
Macrophages contribute to the different phases of mammary gland remodeling during …

Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays

SS Schiffman, EH Scholl, TS Furey… - Journal of Toxicology …, 2023 - Taylor & Francis
The purpose of this study was to determine the toxicological and pharmacokinetic properties
of sucralose-6-acetate, a structural analog of the artificial sweetener sucralose. Sucralose-6 …

[HTML][HTML] The glutathione system: a journey from cyanobacteria to higher eukaryotes

C Cassier-Chauvat, F Marceau, S Farci, S Ouchane… - Antioxidants, 2023 - mdpi.com
From bacteria to plants and humans, the glutathione system plays a pleiotropic role in cell
defense against metabolic, oxidative and metal stresses. Glutathione (GSH), the γ-L …

[HTML][HTML] Immunosuppressive landscape in hepatocellular carcinoma revealed by single-cell sequencing

Y Bai, D Chen, C Cheng, Z Li, H Chi, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background/Aims Hepatocellular carcinoma (HCC), accounting for 75-85% of primary liver
cancer cases, is the third leading cause of cancer-related death worldwide. The purpose of …

[HTML][HTML] Epstein–Barr virus-acquired immunodeficiency in myalgic encephalomyelitis—Is it present in long COVID?

M Ruiz-Pablos, B Paiva, A Zabaleta - Journal of Translational Medicine, 2023 - Springer
Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID
(LC) are characterized by similar immunological alterations, persistence of chronic viral …

Single-cell and spatial transcriptomic analysis of human skin delineates intercellular communication and pathogenic cells

K Thrane, MCG Winge, H Wang, L Chen… - Journal of Investigative …, 2023 - Elsevier
Epidermal homeostasis is governed by a balance between keratinocyte proliferation and
differentiation with contributions from cell–cell interactions, but conserved or divergent …

[HTML][HTML] Multifunctional metallothioneins as a target for neuroprotection in Parkinson's disease

I Miyazaki, M Asanuma - Antioxidants, 2023 - mdpi.com
Parkinson's disease (PD) is characterized by motor symptoms based on a loss of
nigrostriatal dopaminergic neurons and by non-motor symptoms which precede motor …