Nucleus accumbens local circuit for cue-dependent aversive learning

A Belilos, C Gray, C Sanders, D Black, E Mays… - Cell reports, 2023 - cell.com
Response to threatening environmental stimuli requires detection and encoding of important
environmental features that dictate threat. Aversive events are highly salient, which …

α4-containing GABAA receptors on drd2 neurons of the nucleus accumbens mediate instrumental responding for conditioned reinforcers and its potentiation by …

T Macpherson, CI Dixon, J Robertson, MM Sindarto… - Eneuro, 2023 - eneuro.org
Extrasynaptic GABAA receptors (GABAARs) composed of α4, β, and δ subunits mediate
GABAergic tonic inhibition and are potential molecular targets in the modulation of …

Dual roles for nucleus accumbens core dopamine D1-expressing neurons projecting to the substantia nigra pars reticulata in limbic and motor control in male mice

S Attachaipanich, T Ozawa, T Macpherson, T Hikida - Eneuro, 2023 - eneuro.org
The nucleus accumbens (NAc) is a critical component of a limbic basal ganglia circuit that is
thought to play an important role in decision-making and the processing of rewarding stimuli …

Cognitive flexibility in selected animal models of psychiatric disorders

M Janíková - 2023 - dspace.cuni.cz
Cognitive flexibility is the ability to adjust thinking and behavior based on changing
conditions. Cognitive rigidity has been described in a variety of psychiatric and …

行動の柔軟性における側坐核神経回路機構

疋田貴俊 - 日本生物学的精神医学会誌, 2023 - jstage.jst.go.jp
抄録 行動の柔軟性とは, 環境の変化に応じて行動を適応させることを指す. 多くの精神神経疾患
では行動の柔軟性が低下しているため, その神経機構の解明は重要である. 状況に応じた柔軟な …