MiRNA-93: a novel signature in human disorders and drug resistance
Abstract miRNA-93 is a member of the miR-106b-25 family and is encoded by a gene on
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …
WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome
P Wang, J Ma, YC Kim, AY Son… - Proceedings of the …, 2023 - National Acad Sciences
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by various
disabling symptoms including exercise intolerance and is diagnosed in the absence of a …
disabling symptoms including exercise intolerance and is diagnosed in the absence of a …
WASP family proteins: Molecular mechanisms and implications in human disease
Abstract Proteins of the Wiskott-Aldrich syndrome protein (WASP) family play a central role
in regulating actin cytoskeletal dynamics in a wide range of cellular processes. Genetic …
in regulating actin cytoskeletal dynamics in a wide range of cellular processes. Genetic …
The WAVE complex drives the morphogenesis of the photoreceptor outer segment cilium
WJ Spencer, NF Schneider, TR Lewis… - Proceedings of the …, 2023 - National Acad Sciences
The photoreceptor outer segment is a modified cilium filled with hundreds of flattened “disc”
membranes responsible for efficient light capture. To maintain photoreceptor health and …
membranes responsible for efficient light capture. To maintain photoreceptor health and …
ATAD3A: a key regulator of mitochondria-associated diseases
L Chen, Y Li, A Zambidis, V Papadopoulos - International Journal of …, 2023 - mdpi.com
Mitochondrial membrane protein ATAD3A is a member of the AAA-domain-containing
ATPases superfamily. It is important for the maintenance of mitochondrial DNA, structure …
ATPases superfamily. It is important for the maintenance of mitochondrial DNA, structure …
ABI1‐based expression signature predicts breast cancer metastasis and survival
Despite the current standard of care, breast cancer remains one of the leading causes of
mortality in women worldwide, thus emphasizing the need for better predictive and …
mortality in women worldwide, thus emphasizing the need for better predictive and …
The WAVE3/β-catenin oncogenic signaling regulates chemoresistance in triple negative breast cancer
Background Metastatic breast cancer is responsible for the death of the majority of breast
cancer patients. In fact, metastatic BC is the 2nd leading cause of cancer-related deaths in …
cancer patients. In fact, metastatic BC is the 2nd leading cause of cancer-related deaths in …
CRISPRi screen of long non-coding RNAs identifies LINC03045 regulating glioblastoma invasion
K Tsung, KQ Liu, JS Han, K Deshpande, T Doan… - PLoS …, 2024 - journals.plos.org
Introduction Glioblastoma (GBM) invasion studies have focused on coding genes, while few
studies evaluate long non-coding RNAs (lncRNAs), transcripts without protein-coding …
studies evaluate long non-coding RNAs (lncRNAs), transcripts without protein-coding …
SHOX2 cooperates with STAT3 to promote breast cancer metastasis through the transcriptional activation of WASF3
Y Teng, R Loveless, EM Benson, L Sun… - Journal of Experimental …, 2021 - Springer
Background Metastasis is most often the root cause of cancer-related death. Human short
stature homeobox 2 (SHOX2), a homeodomain transcription factor, is a novel inducer of …
stature homeobox 2 (SHOX2), a homeodomain transcription factor, is a novel inducer of …
WASF3 overexpression affects the expression of circular RNA hsa-circ-0100153, which promotes breast cancer progression by sponging hsa-miR-31, hsa-miR-767 …
Background The WASF3 gene has been linked to promoting metastasis in breast cancer
(BC) cells, and low expression reduces invasion potential. Circular RNAs (circRNAs) …
(BC) cells, and low expression reduces invasion potential. Circular RNAs (circRNAs) …