MRI-only based material mass density and relative stopping power estimation via deep learning for proton therapy: a preliminary study

Y Gao, CW Chang, S Mandava, R Marants… - Scientific Reports, 2024 - nature.com
Abstract Magnetic Resonance Imaging (MRI) is increasingly being used in treatment
planning due to its superior soft tissue contrast, which is useful for tumor and soft tissue …

CT-based synthetic contrast-enhanced dual-energy CT generation using conditional denoising diffusion probabilistic model

Y Gao, RLJ Qiu, H Xie, CW Chang… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. The study aimed to generate synthetic contrast-enhanced Dual-energy CT (CE-
DECT) images from non-contrast single-energy CT (SECT) scans, addressing the limitations …

CT‐based synthetic iodine map generation using conditional denoising diffusion probabilistic model

Y Gao, H Xie, CW Chang, J Peng, S Pan… - Medical …, 2024 - Wiley Online Library
Background Iodine maps, derived from image‐processing of contrast‐enhanced dual‐
energy computed tomography (DECT) scans, highlight the differences in tissue iodine …

Recent advances in the clinical applications of machine learning in proton therapy

VL Wildman, JF Wynne, AH Kesarwala, X Yang - medRxiv, 2024 - medrxiv.org
The present systematic review is an effort to explore the different clinical applications and
current implementations of machine/deep learning in proton therapy. It will assist as a …

A deep-learning-based surrogate model for Monte-Carlo simulations of the linear energy transfer in primary brain tumor patients treated with proton-beam …

S Starke, A Kieslich, M Palkowitsch… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. This study explores the use of neural networks (NNs) as surrogate models for
Monte-Carlo (MC) simulations in predicting the dose-averaged linear energy transfer (LET …

Deep learning based linear energy transfer calculation for proton therapy

X Tang, HWC Tseung, D Moseley… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. This study aims to address the limitations of traditional methods for calculating
linear energy transfer (LET), a critical component in assessing relative biological …

Synthetic CT generation from MRI using 3D diffusion model

S Pan, E Abouei, J Wynne, T Wang… - Medical Imaging …, 2024 - spiedigitallibrary.org
This study aims to simplify radiation therapy treatment planning by proposing an MRI-to-CT
transformer-based denoising diffusion probabilistic model (CT-DDPM) to generate high …

Patient-specific 3D volumetric CBCT image reconstruction with single x-ray projection using denoising diffusion probabilistic model

S Pan, SY Lo, CW Chang, E Salari… - Medical Imaging …, 2024 - spiedigitallibrary.org
This study proposes an innovative 3D diffusion-based model called the Cycle-consistency
Geometric-integrated X-ray to Computed Tomography Denoising Diffusion Probabilistic …

Iodine map synthesis from non-contrast CT using diffusion model

Y Gao, H Xie, CW Chang, J Peng, R Qiu… - … 2024: Physics of …, 2024 - spiedigitallibrary.org
Iodine maps can be obtained from contrast enhanced dual-energy compute tomography
(DECT) scans to emphasize iodine contrast agent uptake in cancer patients' tissues, which …

Full-dose PET synthesis from low-dose PET using 2D high efficiency denoising diffusion probabilistic model

S Pan, E Abouei, J Peng, J Qian… - … 2024: Clinical and …, 2024 - spiedigitallibrary.org
The purpose of this study is to reduce radiation exposure in PET imaging while preserving
high-quality clinical PET images. We propose the PET Consistency Model (PET-CM), an …