Structural basis of potential inhibitors targeting SARS-CoV-2 main protease
The Coronavirus disease-19 (COVID-19) pandemic is still devastating the world causing
significant social, economic, and political chaos. Corresponding to the absence of globally …
significant social, economic, and political chaos. Corresponding to the absence of globally …
A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for …
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico …
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a global …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a global …
[HTML][HTML] Drug inhibition of SARS-CoV-2 replication in human pluripotent stem cell–derived intestinal organoids
Background and aims The COVID-19 pandemic has spread worldwide and poses a severe
health risk. While most patients present mild symptoms, descending pneumonia can lead to …
health risk. While most patients present mild symptoms, descending pneumonia can lead to …
Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
Histamine receptors and COVID-19
M Ennis, K Tiligada - Inflammation Research, 2021 - Springer
Objective Reports that the over-the-counter histamine H 2 receptor antagonist famotidine
could help treat the novel coronavirus disease (COVID-19) appeared from April 2020. We …
could help treat the novel coronavirus disease (COVID-19) appeared from April 2020. We …
Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection
Apart from prevention using vaccinations, the management options for COVID-19 remain
limited. In retrospective cohort studies, use of famotidine, a specific oral H2 receptor …
limited. In retrospective cohort studies, use of famotidine, a specific oral H2 receptor …
Omicron SARS-CoV-2 variant spike protein shows an increased affinity to the human ACE2 receptor: an in silico analysis
The rise of SARS-CoV-2 variants, with changes that could be related to an increased virus
pathogenicity, have received the interest of the scientific and medical community. In this …
pathogenicity, have received the interest of the scientific and medical community. In this …
The pathophysiology, diagnosis and treatment of corona virus disease 2019 (COVID-19)
SK Das - Indian Journal of Clinical Biochemistry, 2020 - Springer
Since the beginning of this century, beta coronaviruses (CoV) have caused three zoonotic
outbreaks. However, little is currently known about the biology of the newly emerged SARS …
outbreaks. However, little is currently known about the biology of the newly emerged SARS …
[HTML][HTML] Histamine release theory and roles of antihistamine in the treatment of cytokines storm of COVID-19
OA Eldanasory, K Eljaaly, ZA Memish… - Travel medicine and …, 2020 - ncbi.nlm.nih.gov
In a recent study, authors described therapeutic options for Coronavirus Disease-19 (COVID-
19)[1]. Histamine is an endogenous biogenic amine distributed ubiquitously in the cells and …
19)[1]. Histamine is an endogenous biogenic amine distributed ubiquitously in the cells and …