Postural orthostatic tachycardia syndrome (POTS) is a variant of cardiovascular autonomic
disorder characterized by an excessive heart rate increase on standing and orthostatic …

The clinical use of ivabradine has and continues to evolve along channels that are
predicated on its mechanism of action. It selectively inhibits the funny current (I f) in sinoatrial …

Supraventricular arrhythmias are common and patients are often symptomatic, requiring
management with drugs and electrophysiological procedures. The ESC published …

The recommendations listed in this guideline are, whenever possible, evidence based. An
extensive evidence review was conducted in April 2014 that included literature published …

This document is intended to help front-line cardiologists, arrhythmia specialists, and other
health care professionals interested in the care of patients who present with presumed …

The recommendations listed in this guideline are, whenever possible, evidence based. An
extensive evidence review was conducted in April 2014 that included literature published …

Resting heart rate is central to cardiac output and is influenced by changes occurring in
numerous diseases. It predicts longevity and cardiovascular diseases, and current evidence …

In a family with inappropriate sinus tachycardia (IST), we identified a mutation (p. V240M) of
the hyperpolarization-activated cyclic nucleotide–gated type 4 (HCN4) channel, which …

BBB: bundle branch block bpm: beats per minute CI: confidence interval CL: cycle length
CTI: cavo-tricuspid isthmus DC: direct current ECG: electrocardiogram EPS …

Objective To quantify any risk of atrial fibrillation (AF) associated with ivabradine treatment
by meta-analysis of clinical trial data. Methods Medline, Embase, Web of Knowledge and the …