Neuroinflammation in glaucoma: a new opportunity
PA Williams, N Marsh-Armstrong, GR Howell… - Experimental eye …, 2017 - Elsevier
Mounting evidence suggests neuroinflammation is a key process in glaucoma, yet the
precise roles are not known. Understanding these complex processes, which may also be a …
precise roles are not known. Understanding these complex processes, which may also be a …
Influence of gut microbiota on eye diseases: an overview
P Napolitano, M Filippelli, S Davinelli… - Annals of …, 2021 - Taylor & Francis
The microbiota is a dynamic ecosystem that plays a major role in the host health. Numerous
studies have reported that alterations in the intestinal microbiota (dysbiosis) may contribute …
studies have reported that alterations in the intestinal microbiota (dysbiosis) may contribute …
Transcriptional code and disease map for adult retinal cell types
Brain circuits are assembled from a large variety of morphologically and functionally diverse
cell types. It is not known how the intermingled cell types of an individual adult brain region …
cell types. It is not known how the intermingled cell types of an individual adult brain region …
Targeting oxidative stress for treatment of glaucoma and optic neuritis
A Kimura, K Namekata, X Guo, T Noro… - Oxidative Medicine …, 2017 - Wiley Online Library
Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of
blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells …
blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells …
[HTML][HTML] Normal‑tension glaucoma: Pathogenesis and genetics
A Trivli, I Koliarakis, C Terzidou… - Experimental and …, 2019 - spandidos-publications.com
Normal‑tension glaucoma (NTG) is a multifactorial optic neuropathy which, similar to open‑
angle glaucomas, is characterized by progressive retinal ganglion cell death and …
angle glaucomas, is characterized by progressive retinal ganglion cell death and …
The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
SF Janssen, TGMF Gorgels, WD Ramdas… - Progress in retinal and …, 2013 - Elsevier
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
The genetics of primary open-angle glaucoma: a review
RR Allingham, Y Liu, DJ Rhee - Experimental eye research, 2009 - Elsevier
Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …
[HTML][HTML] Microbiome dysbiosis: a pathological mechanism at the intersection of obesity and glaucoma
S Pezzino, M Sofia, LP Greco, G Litrico… - International Journal of …, 2023 - mdpi.com
The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …
individuals have a high risk of developing elevated intraocular pressure and glaucoma …
[HTML][HTML] An updated review on the genetics of primary open angle glaucoma
K Abu-Amero, AA Kondkar, KV Chalam - International journal of …, 2015 - mdpi.com
Epidemiological studies suggest that by 2020 the prevalence of primary open angle
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …
From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma
Purpose of the study: Many blinding diseases of the inner retina are associated with
degeneration and loss of retinal ganglion cells (RGCs). Recent evidence implicates several …
degeneration and loss of retinal ganglion cells (RGCs). Recent evidence implicates several …