Photochemical and electrochemical strategies in C–F bond activation and functionalization

Z Wang, Y Sun, LY Shen, WC Yang… - Organic Chemistry …, 2022 - pubs.rsc.org
The activation and functionalization of C–F bonds under mild conditions can serve as an
important tool for organic syntheses including the modification of pharmaceuticals and …

Progress in Photoinduced Radical Reactions using Electron Donor‐Acceptor Complexes

L Zheng, L Cai, K Tao, Z Xie, YL Lai… - Asian Journal of …, 2021 - Wiley Online Library
Photocatalyzed organic synthesis transformation is a remarkable green synthetic strategy
because of the advantages of operational simplicity, high chemoselectivities, cheap, and …

Visible‐Light‐Induced Selective Photolysis of Phosphonium Iodide Salts for Monofluoromethylations

Q Liu, Y Lu, H Sheng, CS Zhang, XD Su… - Angewandte Chemie …, 2021 - Wiley Online Library
The sigma (σ)‐hole effect has emerged as a promising tool to construct novel architectures
endowed with new properties. A simple yet effective strategy for the generation of …

Evolution and Future of Hetero‐and Hydro‐Trifluoromethylations of Unsaturated C− C Bonds

S Kawamura, P Barrio, S Fustero… - Advanced Synthesis …, 2023 - Wiley Online Library
The difunctionalizative trifluoromethylation of unsaturated C− C bonds is a highly useful and
efficient method for the synthesis of trifluoromethyl compounds with attractive architectures …

Progress in electrochemical trifluoromethylation reactions

RP Bhaskaran, BP Babu - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
The importance of fluorinated organic molecules in drugs and pharmaceuticals led to the
development of several synthetic methods for introducing fluorine into bioactive molecules …

C–F bond functionalizations of trifluoromethyl groups via radical intermediates

TT Simur, T Ye, YJ Yu, FL Zhang, YF Wang - Chinese Chemical Letters, 2022 - Elsevier
Selective functionalization of C–F bonds in trifluoromethyl groups has recently received a
growing interest, as it offers atom-and step-economic pathways to access highly valuable …

Application of Langlois' reagent (NaSO2CF3) in C–H functionalisation

J Shen, J Xu, L He, C Liang, W Li - Chinese Chemical Letters, 2022 - Elsevier
The process of selectively introducing a CF 3 group into an organic molecule using
inexpensive, stable, and solid sodium trifluoromethanesulfinate has rapidly advanced in …

Strategies toward the difunctionalizations of enamide derivatives for synthesizing α, β-substituted amines

D Bouchet, T Varlet, G Masson - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Enamide and enecarbamate derivatives containing a nucleophilic center at the
β-position from their nitrogen atom as well as a latent electrophilic site at their α-position are …

Pentafluorocyclopropanation of (Hetero) arenes Using Sulfonium Salts: Applications in Late‐Stage Functionalization

Z Feng, L Riemann, Z Guo, D Herrero… - Angewandte …, 2023 - Wiley Online Library
The evaluation of the pentafluorocyclopropyl group as a chemotype in crop protection and
medicinal chemistry has been hampered in the past by the lack of suitable methodologies …

Designing radical chemistry by visible light-promoted homolysis

S Protti, D Ravelli, M Fagnoni - Trends in Chemistry, 2022 - cell.com
The use of visible light to promote synthetic processes has been emerging rapidly in recent
years. In the frame of eco-sustainable strategies involving the generation of reactive …