[HTML][HTML] Pharmacological Evaluation of Cannabinoid Receptor Modulators Using GRABeCB2.0 Sensor

S Shivshankar, J Nimely, H Puhl III, MR Iyer - International Journal of …, 2024 - mdpi.com
Cannabinoid receptors CB1R and CB2R are G-protein coupled receptors acted upon by
endocannabinoids (eCBs), namely 2-arachidonoylglycerol (2-AG) and N-arachidonoyl …

[HTML][HTML] G protein-coupled receptor-biased signaling: potential drug discovery to facilitate treatment of metabolic diseases

S Shen, Q Liao, L Gu, Y Zhu, Y Liu, X Zhang… - Acta Materia …, 2024 - scienceopen.com
G protein-coupled receptors (GPCRs) are important, potential drug targets for the treatment
of metabolic disorders, such as obesity. GPCRs crosstalk with several transducers, including …

[HTML][HTML] Single-cell RNA sequencing reveals the effects of hederasaponin C in the treatment of diabetic nephropathy

J Liu, Q Zhang, W Zhao, J Guo, YK Wong… - Acta Materia …, 2023 - ucl.scienceopen.com
There is great demand for the development of novel efficient therapeutic strategies or
preventative measures to alleviate the life-threatening complications of type 2 diabetes …