Virus DNA replication and the host DNA damage response

MD Weitzman, A Fradet-Turcotte - Annual review of virology, 2018 - annualreviews.org
Viral DNA genomes have limited coding capacity and therefore harness cellular factors to
facilitate replication of their genomes and generate progeny virions. Studies of viruses and …

[HTML][HTML] Human papillomavirus E6 and E7: What remains?

A Vats, O Trejo-Cerro, M Thomas, L Banks - Tumour virus research, 2021 - Elsevier
Decades of research on the human papillomavirus oncogenes, E6 and E7, have given us
huge amounts of data on their expression, functions and structures. We know much about …

[HTML][HTML] Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication

G Garcia, A Sharma, A Ramaiah, C Sen, A Purkayastha… - Cell reports, 2021 - cell.com
SARS-CoV-2 has currently precipitated the COVID-19 global health crisis. We developed a
medium-throughput drug-screening system and identified a small-molecule library of 34 of …

Viral and cellular interactions during adenovirus DNA replication

M Charman, C Herrmann, MD Weitzman - FEBS letters, 2019 - Wiley Online Library
Adenoviruses represent ubiquitous and clinically significant human pathogens, gene‐
delivery vectors, and oncolytic agents. The study of adenovirus‐infected cells has long been …

Kaposi sarcoma herpesvirus pathogenesis

G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …

Human oncogenic viruses: nature and discovery

Y Chang, PS Moore, RA Weiss - … Transactions of the …, 2017 - royalsocietypublishing.org
Seven kinds of virus collectively comprise an important cause of cancer, particularly in less
developed countries and for people with damaged immune systems. Discovered over the …

Nuclear antiviral innate responses at the intersection of DNA sensing and DNA repair

JL Justice, IM Cristea - Trends in microbiology, 2022 - cell.com
The coevolution of vertebrate and mammalian hosts with DNA viruses has driven the ability
of host cells to distinguish viral from cellular DNA in the nucleus to induce intrinsic immune …

Replication compartments of DNA viruses in the nucleus: location, location, location

M Charman, MD Weitzman - Viruses, 2020 - mdpi.com
DNA viruses that replicate in the nucleus encompass a range of ubiquitous and clinically
important viruses, from acute pathogens to persistent tumor viruses. These viruses must co …

SARS-CoV-2 and the DNA damage response

RJ Grand - Journal of General Virology, 2023 - microbiologyresearch.org
The recent coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …

African swine fever virus replication events and cell nucleus: new insights and perspectives

M Simoes, FB Freitas, A Leitao, C Martins, F Ferreira - Virus research, 2019 - Elsevier
African swine fever (ASF) is currently matter for major concerns in global swine industry as it
is highly contagious and causes acute fatal haemorrhagic fever in domestic pigs and wild …