[HTML][HTML] Metabolic regulation of the neural stem cell fate: Unraveling new connections, establishing new concepts

I Angelopoulos, G Gakis, K Birmpas… - Frontiers in …, 2022 - frontiersin.org
The neural stem cell niche is a key regulator participating in the maintenance, regeneration,
and repair of the brain. Within the niche neural stem cells (NSC) generate new neurons …

Transcriptional regulation of multiciliated cell differentiation

M Lewis, TH Stracker - Seminars in cell & developmental biology, 2021 - Elsevier
Multiciliated cells (MCC) project dozens to hundreds of motile cilia from the cell surface to
generate fluid flow across epithelial surfaces or turbulence to promote the transport of …

Posttranslational modification of microtubules by the MATCAP detyrosinase

L Landskron, J Bak, A Adamopoulos, K Kaplani… - Science, 2022 - science.org
The detyrosination-tyrosination cycle involves the removal and religation of the C-terminal
tyrosine of α-tubulin and is implicated in cognitive, cardiac, and mitotic defects. The …

[HTML][HTML] Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain

PP D'Gama, T Qiu, MI Cosacak, D Rayamajhi, A Konac… - Cell reports, 2021 - cell.com
Motile cilia defects impair cerebrospinal fluid (CSF) flow and can cause brain and spine
disorders. The development of ciliated cells, their impact on CSF flow, and their function in …

Ontogeny of adult neural stem cells in the mammalian brain

AM Bond, G Ming, H Song - Current topics in developmental biology, 2021 - Elsevier
Neural stem cells (NSCs) persist into adulthood in the subgranular zone (SGZ) of the
dentate gyrus in the hippocampus and in the ventricular-subventricular zone (V-SVZ) of the …

Motile cilia genetics and cell biology: big results from little mice

L Lee, LE Ostrowski - Cellular and Molecular Life Sciences, 2021 - Springer
Our understanding of motile cilia and their role in disease has increased tremendously over
the last two decades, with critical information and insight coming from the analysis of mouse …

[HTML][HTML] Ependymal and Neural Stem Cells of Adult Molly Fish (Poecilia sphenops, Valenciennes, 1846) Brain: Histomorphometry, Immunohistochemical, and …

DM Mokhtar, RKA Sayed, G Zaccone, M Albano… - Cells, 2022 - mdpi.com
This study was conducted on 16 adult specimens of molly fish (Poecilia sphenops) to
investigate ependymal cells (ECs) and their role in neurogenesis using ultrastructural …

[HTML][HTML] p53/p21 pathway activation contributes to the ependymal fate decision downstream of GemC1

G Ortiz-Álvarez, A Fortoul, A Srivastava, MX Moreau… - Cell Reports, 2022 - cell.com
Multiciliated ependymal cells and adult neural stem cells are components of the adult
neurogenic niche, essential for brain homeostasis. These cells share a common glial cell …

Methods to study motile ciliated cell types in the zebrafish brain

PP D'Gama, N Jurisch-Yaksi - Methods in Cell Biology, 2023 - Elsevier
Cilia are well conserved hair-like structures that have diverse sensory and motile functions.
In the brain, motile ciliated cells, known as ependymal cells, line the cerebrospinal fluid …

[HTML][HTML] Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development

Q Li, Z Han, N Singh, B Terré, RM Fame, U Arif… - Cell Death & …, 2022 - nature.com
Multiciliated cells (MCCs) in the brain reside in the ependyma and the choroid plexus (CP)
epithelia. The CP secretes cerebrospinal fluid that circulates within the ventricular system …