The different facets of dyslipidemia and hypertension in atherosclerosis

J Hurtubise, K McLellan, K Durr, O Onasanya… - Current atherosclerosis …, 2016 - Springer
Atherosclerosis is the narrowing of arteries due to the accumulation of macrophages
overloaded with lipids resulting in foam cell formation, and these events occur preferentially …

Cardiac MRI: a central prognostic tool in myocardial fibrosis

B Ambale-Venkatesh, JAC Lima - Nature Reviews Cardiology, 2015 - nature.com
Fibrotic remodelling of the extracellular matrix is a healing mechanism necessary
immediately after myocardial injury. However, prolonged increase in myocardial fibrotic …

High-sensitive cardiac troponin T as an early biochemical signature for clinical and subclinical heart failure: MESA (Multi-Ethnic Study of Atherosclerosis)

SL Seliger, SN Hong, RH Christenson, R Kronmal… - Circulation, 2017 - Am Heart Assoc
Background: Although small elevations of high-sensitive cardiac troponin T (hs-cTnT) are
associated with incident heart failure (HF) in the general population, the underlying …

Imaging interstitial fibrosis, left ventricular remodeling, and function in stage A and B heart failure

T Pezel, M Viallon, P Croisille, L Sebbag… - Cardiovascular …, 2021 - jacc.org
Myocardial interstitial fibrosis is part of the advanced disease stage of most cardiovascular
pathologies. It has been characterized histologically in various disease settings from …

Pathophysiology of hypertensive heart disease: beyond left ventricular hypertrophy

CC Nwabuo, RS Vasan - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review Given that the life expectancy and the burden of hypertension
are projected to increase over the next decade, hypertensive heart disease (HHD) may be …

Cardiovascular disease among persons living with HIV: new insights into pathogenesis and clinical manifestations in a global context

M Ntsekhe, JV Baker - Circulation, 2023 - Am Heart Assoc
Widespread use of contemporary antiretroviral therapy globally has transformed HIV
disease into a chronic illness associated with excess risk for disorders of the heart and …

Sex-related differences in the extent of myocardial fibrosis in patients with aortic valve stenosis

L Tastet, J Kwiecinski, P Pibarot, R Capoulade… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to assess the effect of sex on myocardial fibrosis as
assessed by using cardiac magnetic resonance (CMR) imaging in aortic stenosis (AS) …

Association between proteomic biomarkers and myocardial fibrosis measured by MRI: the multi-ethnic study of atherosclerosis

H Bakhshi, SA Michelhaugh, SA Bruce, SL Seliger… - …, 2023 - thelancet.com
Background Cardiac magnetic resonance imaging (CMR) determines the extent of interstitial
fibrosis, measured by increased extracellular volume (ECV), and replacement fibrosis with …

Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors

E Dworatzek, S Mahmoodzadeh… - Cardiovascular …, 2019 - academic.oup.com
Aims Sex differences in cardiac fibrosis point to the regulatory role of 17β-Estradiol (E2) in
cardiac fibroblasts (CF). We, therefore, asked whether male and female CF in rodent and …

Association of liver fibrosis with cardiovascular diseases in the general population: the multi-ethnic study of atherosclerosis (MESA)

MR Ostovaneh, B Ambale-Venkatesh… - Circulation …, 2018 - Am Heart Assoc
Background—The association of cardiovascular diseases (CVD) with liver fibrosis is poorly
understood. We aim to assess the association of liver fibrosis by T1-mapping magnetic …