In recent years the amount of experimental data that is produced in biomedical research and
the number of papers that are being published in this field have grown rapidly. In order to …

Proteins are the key players in many cellular processes. Their composition, trafficking, and
interactions underlie the dynamic processes of life. Furthermore, diseases are frequently …

The prevalence of Parkinson's disease (PD) is increasing but the development of novel
treatment strategies and therapeutics altering the course of the disease would benefit from …

Purpose: Noninvasive biomarkers for early detection of pancreatic ductal adenocarcinoma
(PDAC) are currently not available. Here, we aimed to identify a set of urine proteins able to …

Extracellular vesicles (EVs) have a great potential in clinical applications. However, their
isolation from different bodily fluids and their characterisation are currently not optimal or …

Urine is a readily and noninvasively obtainable body fluid. Mass spectrometry (MS)-based
proteomics has shown that urine contains thousands of proteins. Urine is a potential source …

Introduction: Urine is a highly desirable biospecimen for biomarker analysis because it can
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …

The promises of data-independent acquisition (DIA) strategies are a comprehensive and
reproducible digital qualitative and quantitative record of the proteins present in a sample …

Urine is a complex mixture of proteins and waste products and a challenging biological fluid
for biomarker discovery. Previous proteomic studies have identified more than 2800 urinary …

The kidney, urine, and plasma proteomes are intimately related: proteins and metabolic
waste products are filtered from the plasma by the kidney and excreted via the urine, while …