Clinical research in high-income countries is increasingly demonstrating the
costeffectiveness of clinical pharmacogenetic (PGx) testing in reducing the incidence of …

Over the past decades, consistent studies have shown that race/ethnicity have a great
impact on cancer incidence, survival, drug response, molecular pathways and epigenetics …

Colorectal cancer is one of the leading causes of cancer death worldwide. Over the last
decades, several studies have shown that tumor-related genomic alterations predict tumor …

The druggable proteome refers to proteins that can bind to small molecules with appropriate
chemical affinity, inducing a favorable clinical response. Predicting druggable proteins …

Pharmacogenomics (PGx) is considered an emergent field in developing countries.
Research on PGx in the Latin American and the Caribbean (LAC) region remains scarce …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with
the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring …

Breast cancer (BC) is the leading cause of cancer-related death among women and the
most commonly diagnosed cancer worldwide. Although in recent years large-scale efforts …

Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein
expression deregulation, signaling pathway alterations, hormone disruption, ethnicity and …

Breast cancer is the leading cause of cancer‐related death among women worldwide. AKT1
encodes the kinase B alpha protein. The rs121434592, rs12881616, rs11555432 …

Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access
to nutrients due to poor vascularization in the tissue, phenomenon known as hypoxia …