The many roles of PCNA in eukaryotic DNA replication
EM Boehm, MS Gildenberg, MT Washington - The Enzymes, 2016 - Elsevier
Proliferating cell nuclear antigen (PCNA) plays critical roles in many aspects of DNA
replication and replication-associated processes, including translesion synthesis, error-free …
replication and replication-associated processes, including translesion synthesis, error-free …
[HTML][HTML] PCNA, the maestro of the replication fork
GL Moldovan, B Pfander, S Jentsch - Cell, 2007 - cell.com
Inheritance requires genome duplication, reproduction of chromatin and its epigenetic
information, mechanisms to ensure genome integrity, and faithful transmission of the …
information, mechanisms to ensure genome integrity, and faithful transmission of the …
Proliferating cell nuclear antigen (PCNA): a dancer with many partners
G Maga, U Hubscher - Journal of cell science, 2003 - journals.biologists.com
Proliferating cell nuclear antigen (PCNA) was originally characterised as a DNA sliding
clamp for replicative DNA polymerases and as an essential component of the eukaryotic …
clamp for replicative DNA polymerases and as an essential component of the eukaryotic …
Short linear motifs – ex nihilo evolution of protein regulation
Short sequence motifs are ubiquitous across the three major types of biomolecules:
hundreds of classes and thousands of instances of DNA regulatory elements, RNA motifs …
hundreds of classes and thousands of instances of DNA regulatory elements, RNA motifs …
The DNA replication fork in eukaryotic cells
S Waga, B Stillman - Annual review of biochemistry, 1998 - annualreviews.org
Replication of the two template strands at eukaryotic cell DNA replication forks is a highly
coordinated process that ensures accurate and efficient genome duplication. Biochemical …
coordinated process that ensures accurate and efficient genome duplication. Biochemical …
Flap endonuclease 1: a central component of DNA metabolism
Y Liu, HI Kao, RA Bambara - Annual review of biochemistry, 2004 - annualreviews.org
▪ Abstract One strand of cellular DNA is generated as RNA-initiated discontinuous segments
called Okazaki fragments that later are joined. The RNA terminated region is displaced into …
called Okazaki fragments that later are joined. The RNA terminated region is displaced into …
[PDF][PDF] The PCNA-RFC families of DNA clamps and clamp loaders
J Majka, PMJ Burgers - Progress in nucleic acid …, 2004 - burgerslab.biochem.wustl.edu
Progress in Nucleic Acid Research Copyright 2004, Elsevier Inc. and Molecular Biology, Vol.
78 227 All rights reserved. 0079-6603/04 $35.00 modeling. Its modification by ubiquitin …
78 227 All rights reserved. 0079-6603/04 $35.00 modeling. Its modification by ubiquitin …
p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
C Cayrol, M Knibiehler, B Ducommun - Oncogene, 1998 - nature.com
A unique feature of p21 that distinguishes it from the other cyclin-dependent kinase (CDK)
inhibitors is its ability to associate with the proliferating cell nuclear antigen (PCNA), an …
inhibitors is its ability to associate with the proliferating cell nuclear antigen (PCNA), an …
PCNA binding through a conserved motif
E Warbrick - Bioessays, 1998 - Wiley Online Library
Proliferating cell nuclear antigen (PCNA) has recently been identified as a target for the
binding of several proteins. The cell cycle regulatory protein, p21, and the replication …
binding of several proteins. The cell cycle regulatory protein, p21, and the replication …
The puzzle of PCNA's many partners
E Warbrick - Bioessays, 2000 - Wiley Online Library
The identification of proteins that interact with proliferating cell nuclear antigen (PCNA) has
recently been a rapidly expanding field of discovery. PCNA is involved in many aspects of …
recently been a rapidly expanding field of discovery. PCNA is involved in many aspects of …