Mass spectrometry-based metabolomics in microbiome investigations
A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Multi-omics integration in biomedical research–A metabolomics-centric review
Recent advances in high-throughput technologies have enabled the profiling of multiple
layers of a biological system, including DNA sequence data (genomics), RNA expression …
layers of a biological system, including DNA sequence data (genomics), RNA expression …
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
Since its first release over a decade ago, the MetaboAnalyst web-based platform has
become widely used for comprehensive metabolomics data analysis and interpretation …
become widely used for comprehensive metabolomics data analysis and interpretation …
Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial
P Tian, Y Chen, H Zhu, L Wang, X Qian, R Zou… - Brain, behavior, and …, 2022 - Elsevier
Objective Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis,
have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve …
have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve …
Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking
Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …
to measure both known and unknown metabolites in the metabolome. However, unknown …
Lipidomic approaches to dissect dysregulated lipid metabolism in kidney disease
J Baek, C He, F Afshinnia, G Michailidis… - Nature Reviews …, 2022 - nature.com
Dyslipidaemia is a hallmark of chronic kidney disease (CKD). The severity of dyslipidaemia
not only correlates with CKD stage but is also associated with CKD-associated …
not only correlates with CKD stage but is also associated with CKD-associated …
Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility
M Kameda, T Teruya, M Yanagida… - Proceedings of the …, 2020 - National Acad Sciences
As human society ages globally, age-related disorders are becoming increasingly common.
Due to decreasing physiological reserves and increasing organ system dysfunction …
Due to decreasing physiological reserves and increasing organ system dysfunction …
Network-based strategies in metabolomics data analysis and interpretation: from molecular networking to biological interpretation
Introduction Metabolomics has become a crucial part of systems biology; however, data
analysis is still often undertaken in a reductionist way focusing on changes in individual …
analysis is still often undertaken in a reductionist way focusing on changes in individual …
Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan‐produced indole metabolites
H Miao, YN Wang, XY Yu, L Zou, Y Guo… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Membranous nephropathy (MN) is an immune‐mediated
glomerular disease in adults. Antibody‐and antigen‐bonding mechanisms have been …
glomerular disease in adults. Antibody‐and antigen‐bonding mechanisms have been …