Mechanical studies of the third dimension in cancer: From 2D to 3D model

F Paradiso, S Serpelloni, LW Francis… - International Journal of …, 2021 - mdpi.com
From the development of self-aggregating, scaffold-free multicellular spheroids to the
inclusion of scaffold systems, 3D models have progressively increased in complexity to …

Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back

P Wolujewicz, JW Steele, JA Kaltschmidt, RH Finnell… - Genesis, 2021 - Wiley Online Library
Neural tube defects (NTDs) are a classic example of preventable birth defects for which
there is a proven‐effective intervention, folic acid (FA); however, further methods of …

[HTML][HTML] An osteogenic bioink composed of alginate, cellulose nanofibrils, and polydopamine nanoparticles for 3D bioprinting and bone tissue engineering

S Im, G Choe, JM Seok, SJ Yeo, JH Lee… - International Journal of …, 2022 - Elsevier
Bioprinting is an emerging technology for manufacturing cell-laden three-dimensional (3D)
scaffolds, which are used to fabricate complex 3D constructs and provide specific …

Remotely Actuated Magnetic Nanocarpets for Bone Tissue Engineering: Non‐Invasive Modulation of Mechanosensitive Ion Channels for Enhanced Osteogenesis

AR Unnithan, ARK Sasikala… - Advanced Functional …, 2022 - Wiley Online Library
Non‐invasive approaches using remotely controllable nanomaterials have demonstrated
their potential ability to enhance treatment efficacy in regenerative medicine and tissue …

Emerging role and promise of nanomaterials in organoid research

C Mahapatra, R Lee, MK Paul - Drug Discovery Today, 2022 - Elsevier
Organoids are 3D stem cell-derived self-organization of cells. Organoid bioengineering
helps recreate and tailor their architecture in vitro to generate mini organ-like properties …

Recent advances in brain organoid technology for human brain research

E Jeong, S Choi, SW Cho - ACS Applied Materials & Interfaces, 2022 - ACS Publications
Brain organoids are self-assembled three-dimensional aggregates with brain-like cell types
and structures and have emerged as new model systems that can be used to investigate …

Low forces push the maturation of neural precursors into neurons

S De Vincentiis, M Baggiani, F Merighi, V Cappello… - Small, 2023 - Wiley Online Library
Mechanical stimulation modulates neural development and neuronal activity. In a previous
study, magnetic “nano‐pulling” is proposed as a tool to generate active forces. By loading …

Organoids: A new approach in toxicity testing of nanotherapeutics

SU Nabi, SI Ali, MA Rather, WM Sheikh… - Journal of Applied …, 2022 - Wiley Online Library
Nanotechnology has revolutionized diverse fields, which include agriculture, the consumer
market, medicine, and other fields. Widespread use of nanotechnology‐based products has …

[HTML][HTML] Magnetic colloidal nanoformulations to remotely trigger mechanotransduction for osteogenic differentiation

M Estévez, M Cicuéndez, M Colilla… - Journal of Colloid and …, 2024 - Elsevier
Nowadays, diseases associated with an ageing population, such as osteoporosis, require
the development of new biomedical approaches to bone regeneration. In this regard …

Nanomaterial additives for fabrication of stimuli‐responsive skeletal muscle tissue engineering constructs

AC Farr, KJ Hogan, AG Mikos - Advanced Healthcare Materials, 2020 - Wiley Online Library
Volumetric muscle loss necessitates novel tissue engineering strategies for skeletal muscle
repair, which have traditionally involved cells and extracellular matrix‐mimicking scaffolds …