Most acute coronary syndromes are caused by sudden luminal thrombosis due to
atherosclerotic plaque rupture or erosion. Preventing such an event seems to be the only …

Low and oscillatory wall shear stress is widely assumed to play a key role in the initiation
and development of atherosclerosis. Indeed, some studies have relied on the low shear …

Cardiovascular diseases are the leading cause of mortality, morbidity, and hospitalization
around the world. Recent technological advances have facilitated analyzing, visualizing …

Aims Atherosclerotic plaque development has been associated with wall shear stress
(WSS). However, the multidirectionality of blood flow, and thus of WSS, is rarely taken into …

Coronary plaque rupture is the most common cause of vessel thrombosis and acute
coronary syndrome. The accurate early detection of plaques prone to rupture may allow …

Although unphysiological wall shear stress (WSS) has become the consensus
hemodynamic mechanism for coronary atherosclerosis, the complex biomechanical stimulus …

Background—Despite the exposure of the entire vasculature to the atherogenic effects of
systemic risk factors, atherosclerotic plaques preferentially develop at sites with disturbed …

Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

Wall shear stress (WSS), the frictional force of the blood on the vessel wall, plays a crucial
role in atherosclerotic plaque development. Low WSS has been associated with plaque …

Atherosclerosis develops due to different hemodynamic factors, among which time-
averaged Wall shear stress (mean WSS) and Oscillatory shear index (OSI) are two of the …