Gadolinium deposition in brain: current scientific evidence and future perspectives
BJ Guo, ZL Yang, LJ Zhang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
In the past 4 years, many publications described a concentration-dependent deposition of
gadolinium in the brain both in adults and children, seen as high signal intensities in the …
gadolinium in the brain both in adults and children, seen as high signal intensities in the …
Gadolinium deposition in the brain: current updates
JW Choi, WJ Moon - Korean journal of radiology, 2019 - synapse.koreamed.org
Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …
imaging and have long been considered safe when administered at recommended doses …
Current and future MR contrast agents: seeking a better chemical stability and relaxivity for optimal safety and efficacy
E Lancelot, JS Raynaud, P Desché - Investigative radiology, 2020 - journals.lww.com
This review summarizes 30 years of experience in the development and clinical use of
magnetic resonance (MR) contrast agents. Despite their undisputable usefulness for …
magnetic resonance (MR) contrast agents. Despite their undisputable usefulness for …
Deep learning–based methods may minimize GBCA dosage in brain MRI
Objectives To evaluate the clinical performance of a deep learning (DL)–based method for
brain MRI exams with reduced gadolinium-based contrast agent (GBCA) dose to provide …
brain MRI exams with reduced gadolinium-based contrast agent (GBCA) dose to provide …
Pharmacokinetics, safety, and efficacy of gadopiclenol in pediatric patients aged 2 to 17 years
E Jurkiewicz, S Tsvetkova, A Grinberg… - Investigative …, 2022 - journals.lww.com
Objectives The aim of this study was to evaluate the pharmacokinetic (PK) profile, safety,
and efficacy of gadopiclenol, a new high-relaxivity gadolinium-based contrast agent, in …
and efficacy of gadopiclenol, a new high-relaxivity gadolinium-based contrast agent, in …
Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents
L Chehabeddine, T Al Saleh, M Baalbaki… - Critical Reviews in …, 2019 - Taylor & Francis
Ever since gadolinium was found to deposit in the brain of patients with normal kidney
function by Kanda et al. in 2014, several studies have been conducted to evaluate its effect …
function by Kanda et al. in 2014, several studies have been conducted to evaluate its effect …
Safety of gadolinium administration in children
I Elbeshlawi, MS AbdelBaki - Pediatric Neurology, 2018 - Elsevier
The introduction of paramagnetic contrast in the late 1980s constituted a paradigm shift
boosting the efficacy of magnetic resonance imaging. Due to its high magnetic moment …
boosting the efficacy of magnetic resonance imaging. Due to its high magnetic moment …
How the chemical properties of GBCAs influence their safety profiles in vivo
The extracellular class of gadolinium-based contrast agents (GBCAs) is an essential tool for
clinical diagnosis and disease management. In order to better understand the issues …
clinical diagnosis and disease management. In order to better understand the issues …
Comparative study between functional MR urography and renal scintigraphy to evaluate drainage curves and split renal function in children with congenital anomalies …
MB Damasio, M Bodria, M Dolores, E Durand… - Frontiers in …, 2020 - frontiersin.org
Background: Obstructive congenital anomalies of the kidney and urinary tract have a high
risk of kidney failure if not surgically corrected. Dynamic renal scintigraphy is the gold …
risk of kidney failure if not surgically corrected. Dynamic renal scintigraphy is the gold …
[HTML][HTML] Reliability of signal intensity in the basal ganglia on non-contrast T1-weighted MR scans after repetitive application of a gadolinium-based contrast agent in …
A Hojreh, A Mulabdic, J Furtner, C Krall… - European Journal of …, 2023 - Elsevier
Purpose To evaluate the reliability of signal intensity (SI) changes in the basal ganglia as a
supposed indicator of gadolinium deposition in the brain after repetitive application of …
supposed indicator of gadolinium deposition in the brain after repetitive application of …