Microbial genes and pathways in inflammatory bowel disease

M Schirmer, A Garner, H Vlamakis… - Nature Reviews …, 2019 - nature.com
Perturbations in the intestinal microbiome are implicated in inflammatory bowel disease
(IBD). Studies of treatment-naive patients have identified microbial taxa associated with …

Macrophage immunometabolism in inflammatory bowel diseases: from pathogenesis to therapy

X Pan, Q Zhu, LL Pan, J Sun - Pharmacology & therapeutics, 2022 - Elsevier
Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is a
chronic relapsing inflammatory disease of the gastrointestinal tract that closely related to …

[HTML][HTML] MetaboAnalystR 3.0: toward an optimized workflow for global metabolomics

Z Pang, J Chong, S Li, J Xia - Metabolites, 2020 - mdpi.com
Liquid chromatography coupled to high-resolution mass spectrometry platforms are
increasingly employed to comprehensively measure metabolome changes in systems …

Berberine improves colitis by triggering AhR activation by microbial tryptophan catabolites

W Jing, S Dong, X Luo, J Liu, B Wei, W Du… - Pharmacological …, 2021 - Elsevier
Inflammatory bowel diseases (IBD) are kind of recurrent inflammatory issues that occur in
the gastrointestinal tract, and currently clinical treatment is still unideal due to the complex …

[HTML][HTML] Serum biomarkers for inflammatory bowel disease

P Chen, G Zhou, J Lin, L Li, Z Zeng, M Chen… - Frontiers in …, 2020 - frontiersin.org
Background: Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative
colitis, is a chronic, inflammatory disorder of the gastrointestinal tract. As the novel …

Metabolomic analysis in inflammatory bowel disease: a systematic review

K Gallagher, A Catesson, JL Griffin… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims The inflammatory bowel diseases [IBD], Crohn's disease and
ulcerative colitis, are chronic, idiopathic gastrointestinal diseases. Although their precise …

[HTML][HTML] The role of dietary nutrients in inflammatory bowel disease

K Sugihara, TL Morhardt, N Kamada - Frontiers in immunology, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disease of the
gastrointestinal tract. Although the precise etiology of IBD remains incompletely understood …

[HTML][HTML] Manipulating microbiota in inflammatory bowel disease treatment: Clinical and natural product interventions explored

M Zhu, Y Song, Y Xu, H Xu - International journal of molecular sciences, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a complex multifactorial chronic inflammatory disease,
that includes Crohn's disease (CD) and ulcerative colitis (UC), having progressively …

[HTML][HTML] Mechanisms and regulation of defensins in host defense

J Fu, X Zong, M Jin, J Min, F Wang… - Signal Transduction and …, 2023 - nature.com
As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Metabolomic epidemiology offers insights into disease aetiology

H Fuller, Y Zhu, J Nicholas, HA Chatelaine… - Nature …, 2023 - nature.com
Metabolomic epidemiology is the high-throughput study of the relationship between
metabolites and health-related traits. This emerging and rapidly growing field has improved …