In this review, we summarize studies investigating the types and distribution of voltage-and
calcium-gated ion channels in the different classes of retinal neurons: rods, cones …

The mammalian retina is the most unique tissue among those that display robust
circadian/diurnal oscillations. The retina is not only a light sensing tissue that relays light …

Mounting evidence suggests that voltage-gated L-type Ca2+ channels can modulate
affective behaviour. We therefore explored the role of CaV1. 3 L-type Ca2+ channels in …

Rod and cone photoreceptors possess ribbon synapses that assist in the transmission of
graded light responses to second-order bipolar and horizontal cells of the vertebrate retina …

Voltage-gated Ca2+ channels (VGCCs) mediate Ca2+ influx to trigger neurotransmitter
release at specialized presynaptic sites termed active zones (AZs). The abundance of …

At most synapses, presynaptic Ca2+ channels are positioned near vesicle release sites, and
increasing this distance reduces synaptic strength. We examined the lateral membrane …

Mutations in the CACNA1F gene encoding the Cav1. 4 Ca2+ channel are associated with X-
linked congenital stationary night blindness type 2 (CSNB2). Despite the increasing …

A rise in intracellular calcium levels ([Ca2+] i) is a key trigger for the lethal effects of the
excitatory neurotransmitter glutamate in various central neurons, but a consensus has not …

The cortical cytoskeleton is a dense network of filamentous actin (F-actin) that participates in
the events associated with secretion from neuroendocrine cells. This filamentous web traps …

Alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonists can prevent glutamate-
induced excitotoxicity in cultured retinal ganglion cells (RGCs). However, the …