The genetics of obesity: from discovery to biology

RJF Loos, GSH Yeo - Nature Reviews Genetics, 2022 - nature.com
The prevalence of obesity has tripled over the past four decades, imposing an enormous
burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset …

A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

From NASH to HCC: current concepts and future challenges

QM Anstee, HL Reeves, E Kotsiliti, O Govaere… - Nature reviews …, 2019 - nature.com
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …

[HTML][HTML] Assessing the age specificity of infection fatality rates for COVID-19: systematic review, meta-analysis, and public policy implications

AT Levin, WP Hanage, N Owusu-Boaitey… - European journal of …, 2020 - Springer
Determine age-specific infection fatality rates for COVID-19 to inform public health policies
and communications that help protect vulnerable age groups. Studies of COVID-19 …

[HTML][HTML] Ожирение

ИИ Дедов, НГ Мокрышева, ГА Мельниченко… - Consilium …, 2021 - cyberleninka.ru
В декабре 2020 г. Научно-практическим советом Минздрава России были утверждены
клинические рекомендации «Ожирение», разработанные Российской ассоциацией …

[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

NASH leading cause of liver transplant in women: updated analysis of indications for liver transplant and ethnic and gender variances

M Noureddin, A Vipani, C Bresee, T Todo… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Chronic infection with hepatitis C virus (HCV) was previously the leading
indication for liver transplant (LT) in the United States. However, since 2014 the use of direct …

Cellular senescence drives age-dependent hepatic steatosis

M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos… - Nature …, 2017 - nature.com
The incidence of non-alcoholic fatty liver disease (NAFLD) increases with age. Cellular
senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

[HTML][HTML] Междисциплинарные клинические рекомендации «Лечение ожирения и коморбидных заболеваний»

ИИ Дедов, МВ Шестакова… - Ожирение и …, 2021 - cyberleninka.ru
Клинические рекомендации уже давно вошли в число рабочих инструментов
современного врача, помогая ему быстро ориентироваться в наиболее эффективных …