Biomechanical, biophysical and biochemical modulators of cytoskeletal remodelling and emergent stem cell lineage commitment

VDL Putra, KA Kilian, ML Knothe Tate - Communications Biology, 2023 - nature.com
Across complex, multi-time and-length scale biological systems, redundancy confers
robustness and resilience, enabling adaptation and increasing survival under dynamic …

Synthetic biodegradable functional polymers for tissue engineering: a brief review

BL Guo, PX Ma - Science China Chemistry, 2014 - Springer
Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great
processing flexibility are the predominant scaffolding materials. Synthetic biodegradable …

Osteoblast and osteocyte: games without frontiers

M Capulli, R Paone, N Rucci - Archives of biochemistry and biophysics, 2014 - Elsevier
The portrait of osteoblasts and osteocytes has been subjected to a revision, since a large
body of evidence is attributing these cells amazing roles both inside and outside the bone …

Intrinsic mechanical cues and their impact on stem cells and embryogenesis

J Petzold, E Gentleman - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Although understanding how soluble cues direct cellular processes revolutionised the study
of cell biology in the second half of the 20th century, over the last two decades, new insights …

Current insights on the regenerative potential of the periosteum: molecular, cellular, and endogenous engineering approaches

C Colnot, X Zhang, MLK Tate - Journal of Orthopaedic …, 2012 - Wiley Online Library
While century old clinical reports document the periosteum's remarkable regenerative
capacity, only in the past decade have scientists undertaken mechanistic investigations of its …

The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells

DJ Kelly, CR Jacobs - Birth Defects Research Part C: Embryo …, 2010 - Wiley Online Library
It is becoming increasingly clear that mesenchymal stem cell (MSC) differentiation is
regulated by mechanical signals. Mechanical forces generated intrinsically within the cell in …

Biomechanical determinants of the stability of dental implants: Influence of the bone–implant interface properties

V Mathieu, R Vayron, G Richard, G Lambert… - Journal of …, 2014 - Elsevier
Dental implants are now widely used for the replacement of missing teeth in fully or partially
edentulous patients and for cranial reconstructions. However, risks of failure, which may …

Concise review: the periosteum: tapping into a reservoir of clinically useful progenitor cells

H Chang, ML Knothe Tate - Stem cells translational medicine, 2012 - academic.oup.com
Elucidation of the periosteum and its regenerative potential has become a hot topic in
orthopedics. Yet few review articles address the unique features of periosteum-derived cells …

Flow-induced stress on adherent cells in microfluidic devices

J Shemesh, I Jalilian, A Shi, GH Yeoh, MLK Tate… - Lab on a Chip, 2015 - pubs.rsc.org
Transduction of mechanical forces and chemical signals affect every cell in the human body.
Fluid flow in systems such as the lymphatic or circulatory systems modulates not only cell …

The response of bone marrow-derived mesenchymal stem cells to dynamic compression following TGF-β3 induced chondrogenic differentiation

SD Thorpe, CT Buckley, T Vinardell, FJ O'Brien… - Annals of biomedical …, 2010 - Springer
The objective of this study was to investigate the hypothesis that the application of dynamic
compression following transforming growth factor-β3 (TGF-β3) induced differentiation will …