[HTML][HTML] The research progress in immunotherapy of tuberculosis

J Mi, Y Liang, J Liang, W Gong, S Wang… - Frontiers in cellular …, 2021 - frontiersin.org
Tuberculosis (TB) is a serious public health problem worldwide. The combination of various
anti-TB drugs is mainly used to treat TB in clinical practice. Despite the availability of …

The Use of Particulate Systems for Tuberculosis Prophylaxis and Treatment: Opportunities and Challenges

A Barrera-Rosales, R Rodríguez-Sanoja… - Microorganisms, 2023 - mdpi.com
The use of particles to develop vaccines and treatments for a wide variety of diseases has
increased, and their success has been demonstrated in preclinical investigations. Accurately …

Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection

AC Rothchild, B Stowell, G Goyal, C Nunes-Alves… - MBio, 2017 - Am Soc Microbiol
Mice deficient for granulocyte-macrophage colony-stimulating factor (GM-CSF−/−) are highly
susceptible to infection with Mycobacterium tuberculosis, and clinical data have shown that …

Extracellular vesicles released by J774A. 1 macrophages reduce the bacterial load in macrophages and in an experimental mouse model of tuberculosis

M García-Martínez, L Vázquez-Flores… - International Journal …, 2019 - Taylor & Francis
Background Tuberculosis is the leading cause of death by an infectious microorganism
worldwide. Conventional treatment lasts at least six months and has adverse effects; …

Mycobacterium tuberculosis: immune response, biomarkers, and therapeutic intervention

L Zhuang, L Yang, L Li, Z Ye, W Gong - MedComm, 2024 - Wiley Online Library
Although tuberculosis (TB) is an infectious disease, the progression of the disease following
Mycobacterium tuberculosis (MTB) infection is closely associated with the host's immune …

[HTML][HTML] Understanding the reciprocal interplay between antibiotics and host immune system: how can we improve the anti-mycobacterial activity of current drugs to …

HE Park, W Lee, MK Shin, SJ Shin - Frontiers in Immunology, 2021 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, remains a global
health threat despite recent advances and insights into host-pathogen interactions and the …

[HTML][HTML] Expressions of miR-29a, TNF-Α and vascular endothelial growth factor in peripheral blood of pulmonary tuberculosis patients and their clinical significance

LI Zhenyu, LI Chunlin, BAO Ruri… - Iranian journal of public …, 2020 - ncbi.nlm.nih.gov
Background: To investigate the expression levels of miRNA-29a (miR-29a), tumor necrosis
factor-α (TNF-α) and vascular endothelial growth factor (VEGF) in peripheral blood of …

T cell production of GM-CSF protects the host during experimental tuberculosis

RT Robinson - MBio, 2017 - Am Soc Microbiol
Although classically associated with myelopoiesis, granulocyte-macrophage colony-
stimulating factor (GM-CSF) is increasingly recognized as being important for tuberculosis …

Gene therapy based in antimicrobial peptides and proinflammatory cytokine prevents reactivation of experimental latent tuberculosis

O Ramos-Espinosa… - FEMS Pathogens …, 2016 - academic.oup.com
Mycobacterium tuberculosis (Mtb) latent infection can lead to reactivation. The design of new
strategies to prevent it is an important subject. B6D2F1 mice were infected intratracheally …

Immunotherapeutic effect of adenovirus encoding antimicrobial peptides in experimental pulmonary tuberculosis

O Ramos-Espinosa, D Mata-Espinosa… - Journal of Leukocyte …, 2021 - academic.oup.com
As components of the innate immune response, antimicrobial peptides (AMPs) efficiently
contribute to infection control and maintenance of a latent state in pulmonary tuberculosis …