Resveratrol (RV) is a well-known polyphenolic compound in various plants, including grape,
peanut, and berry fruits, which is quite famous for its association with several health benefits …

Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old.
The molecular and cellular alterations that trigger this disease are still diffuse, one of the …

Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

Molecular hybridization is a well-exploited medicinal chemistry strategy that aims to combine
two molecules (or parts of them) in a new, single chemical entity. Recently, it has been …

Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …

Alzheimer's disease is a chronic neurodegenerative disorder characterized by a progressive
loss of cognitive and behavioral abilities. Extracellular senile plaques and intracellular …

Alzheimer's disease (AD) is the leading cause of dementia in the elderly and is
characterized by progressive cognitive and memory deficits. The pathological hallmarks of …

A series of multitarget-directed resveratrol derivatives was designed and synthesized for the
treatment of Alzheimer's disease (AD). In vitro studies indicated that most of the target …

Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …