Phase transitions and size scaling of membrane-less organelles
CP Brangwynne - Journal of Cell Biology, 2013 - rupress.org
The coordinated growth of cells and their organelles is a fundamental and poorly
understood problem, with implications for processes ranging from embryonic development …
understood problem, with implications for processes ranging from embryonic development …
The lamin protein family
TA Dittmer, T Misteli - Genome biology, 2011 - Springer
The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the
inside of the nuclear membrane, where they provide a platform for the binding of proteins …
inside of the nuclear membrane, where they provide a platform for the binding of proteins …
The nuclear-to-cytoplasmic ratio: coupling DNA content to cell size, cell cycle, and biosynthetic capacity
S Balachandra, S Sarkar… - Annual review of genetics, 2022 - annualreviews.org
Though cell size varies between different cells and across species, the nuclear-to-
cytoplasmic (N/C) ratio is largely maintained across species and within cell types. A cell …
cytoplasmic (N/C) ratio is largely maintained across species and within cell types. A cell …
C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import
Disruption of nucleocytoplasmic transport is increasingly implicated in the pathogenesis of
neurodegenerative diseases, including ALS caused by a C9orf72 hexanucleotide repeat …
neurodegenerative diseases, including ALS caused by a C9orf72 hexanucleotide repeat …
What determines cell size?
© 2012 Marshall et al; licensee BioMed Central Ltd. This is an Open Access article
distributed under the terms of the Creative Commons Attribution License (http …
distributed under the terms of the Creative Commons Attribution License (http …
Balance of osmotic pressures determines the nuclear-to-cytoplasmic volume ratio of the cell
The volume of the cell nucleus varies across cell types and species and is commonly
thought to be determined by the size of the genome and degree of chromatin compaction …
thought to be determined by the size of the genome and degree of chromatin compaction …
Importin α: functions as a nuclear transport factor and beyond
M Oka, Y Yoneda - Proceedings of the Japan Academy, Series B, 2018 - jstage.jst.go.jp
Nucleocytoplasmic transport is an essential process in eukaryotes. The molecular
mechanisms underlying nuclear transport that involve the nuclear transport receptor, small …
mechanisms underlying nuclear transport that involve the nuclear transport receptor, small …
Unravelling nuclear size control
H Cantwell, P Nurse - Current genetics, 2019 - Springer
Correlation between nuclear and cell size, the nucleocytoplasmic ratio, is a cellular
phenomenon that has been reported throughout eukaryotes for more than a century but the …
phenomenon that has been reported throughout eukaryotes for more than a century but the …
Coordinating genome expression with cell size
S Marguerat, J Bähler - Trends in Genetics, 2012 - cell.com
Cell size is highly variable; cells from various tissues differ in volume over orders of
magnitudes, from tiny lymphocytes to giant neurons, and cells of a given type change size …
magnitudes, from tiny lymphocytes to giant neurons, and cells of a given type change size …
Control of nuclear size by osmotic forces in Schizosaccharomyces pombe
The size of the nucleus scales robustly with cell size so that the nuclear-to-cell volume ratio
(N/C ratio) is maintained during cell growth in many cell types. The mechanism responsible …
(N/C ratio) is maintained during cell growth in many cell types. The mechanism responsible …