Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians

D Moris, M Palta, C Kim, PJ Allen… - CA: a cancer journal …, 2023 - Wiley Online Library
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver tumor and
remains a fatal malignancy in the majority of patients. Approximately 20%–30% of patients …

Cholangiocarcinoma

PJ Brindley, M Bachini, SI Ilyas, SA Khan… - Nature reviews Disease …, 2021 - nature.com
Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system,
which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has …

Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer …

RK Kelley, M Ueno, C Yoo, RS Finn, J Furuse, Z Ren… - The Lancet, 2023 - thelancet.com
Background Biliary tract cancers, which arise from the intrahepatic or extrahepatic bile ducts
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide …

Biliary tract cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up☆

A Vogel, J Bridgewater, J Edeline… - Annals of …, 2023 - annalsofoncology.org
Biliary tract cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆ -
Annals of Oncology Skip to Main Content Advertisement Annals of Oncology European Society …

Adjuvant S-1 compared with observation in resected biliary tract cancer (JCOG1202, ASCOT): a multicentre, open-label, randomised, controlled, phase 3 trial

K Nakachi, M Ikeda, M Konishi, S Nomura, H Katayama… - The Lancet, 2023 - thelancet.com
Background S-1 has shown promising efficacy with a mild toxicity profile in patients with
advanced biliary tract cancer. The aim of this study was to evaluate whether adjuvant S-1 …

Gallbladder cancer

JC Roa, P García, VK Kapoor, SK Maithel… - Nature reviews Disease …, 2022 - nature.com
Gallbladder cancer (GBC) is the most common cancer of the biliary tract, characterized by a
very poor prognosis when diagnosed at advanced stages owing to its aggressive behaviour …

Current and emerging therapies for advanced biliary tract cancers

AE Kam, A Masood, RT Shroff - The lancet Gastroenterology & …, 2021 - thelancet.com
Biliary tract cancers (cholangiocarcinomas and gallbladder cancers) are increasing in
incidence and have a poor prognosis. Most patients present with advanced disease, for …

Randomized phase III study of gemcitabine, cisplatin plus S‐1 versus gemcitabine, cisplatin for advanced biliary tract cancer (KHBO1401‐MITSUBA)

T Ioka, M Kanai, S Kobayashi, D Sakai… - Journal of Hepato …, 2023 - Wiley Online Library
Background Gemcitabine/cisplatin (GC) combination therapy has been the standard
palliative chemotherapy for patients with advanced biliary tract cancer (BTC). No …

Clinical practice guidelines for the management of biliary tract cancers 2019: The 3rd English edition

M Nagino, S Hirano, H Yoshitomi, T Aoki… - Journal of Hepato …, 2021 - Wiley Online Library
Abstract Background The Japanese Society of Hepato‐Biliary‐Pancreatic Surgery launched
the clinical practice guidelines for the management of biliary tract cancers …

Biliary tract cancer

JW Valle, RK Kelley, B Nervi, DY Oh, AX Zhu - The Lancet, 2021 - thelancet.com
Biliary tract cancers, including intrahepatic, perihilar, and distal cholangiocarcinoma as well
as gallbladder cancer, are low-incidence malignancies in most high-income countries, but …