How does high DHA fish oil affect health? A systematic review of evidence

S Ghasemi Fard, F Wang, AJ Sinclair… - Critical reviews in …, 2019 - Taylor & Francis
The health benefits of fish oil, and its omega-3 long chain polyunsaturated fatty acid content,
have attracted much scientific attention in the last four decades. Fish oils that contain higher …

Management of hypertriglyceridemia

V Simha - bmj, 2020 - bmj.com
Hypertriglyceridemia is one of the most common lipid abnormalities encountered in clinical
practice. Many monogenic disorders causing severe hypertriglyceridemia have been …

Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases

WH Schunck, A Konkel, R Fischer… - Pharmacology & …, 2018 - Elsevier
Numerous benefits have been attributed to dietary long-chain omega-3 polyunsaturated fatty
acids (n-3 LC-PUFAs), including protection against cardiac arrhythmia, triglyceride-lowering …

The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiometabolic risk factors: a systematic review

JK Innes, PC Calder - International journal of molecular sciences, 2018 - mdpi.com
A large body of evidence supports the cardioprotective effects of the long-chain omega-3
polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA), and docosahexaenoic …

Intake and metabolism of omega-3 and omega-6 polyunsaturated fatty acids: nutritional implications for cardiometabolic diseases

MB Schulze, AM Minihane, RNM Saleh… - The Lancet Diabetes & …, 2020 - thelancet.com
Prospective observational studies support the use of long-chain omega-3 polyunsaturated
fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; …

The role of n-3 PUFA-derived fatty acid derivatives and their oxygenated metabolites in the modulation of inflammation

I de Bus, R Witkamp, H Zuilhof, B Albada… - Prostaglandins & other …, 2019 - Elsevier
Notwithstanding the ongoing debate on their full potential in health and disease, there is
general consensus that n-3 PUFAs play important physiological roles. Increasing dietary n-3 …

High-dose omega-3 polyunsaturated fatty acid supplementation might be more superior than low-dose for major depressive disorder in early therapy period: a network …

X Luo, J Feng, Z Yang, Q Huang, J Lin, B Yang, K Su… - BMC psychiatry, 2020 - Springer
Background The application of n-3 Polyunsaturated Fatty Acids (n-3 PUFAs)
supplementation for major depressive disorder (MDD) has been widely discussed in recent …

Dietary ALA, EPA and DHA have distinct effects on oxylipin profiles in female and male rat kidney, liver and serum

S Leng, T Winter, HM Aukema - The Journal of nutritional biochemistry, 2018 - Elsevier
There is much data on the effects of dietary n-3 fatty acids on tissue fatty acid compositions,
but comparable comprehensive data on their oxygenated metabolites (oxylipins) is limited …

Carbohydrate intake attenuates post-exercise plasma levels of cytochrome P450-generated oxylipins

DC Nieman, ND Gillitt, GY Chen, Q Zhang… - PLoS …, 2019 - journals.plos.org
Introduction Oxylipins are bioactive oxidation products derived from n-6 and n-3
polyunsaturated fatty acids (PUFAs) in the linoleic acid and α-linolenic desaturation …

Effect of DHA supplementation on oxylipin levels in plasma and immune cell stimulated blood

JP Schuchardt, AI Ostermann, L Stork, S Fritzsch… - … and Essential Fatty …, 2017 - Elsevier
Introduction EPA and DHA cause different physiological effects, which are in many cases
mediated via their oxidative metabolites (oxylipins). However, metabolism studies …