Combating mosquito-borne diseases using genetic control technologies

GH Wang, S Gamez, RR Raban, JM Marshall… - Nature …, 2021 - nature.com
Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …

Controlling vector-borne diseases by releasing modified mosquitoes

HA Flores, SL O'Neill - Nature Reviews Microbiology, 2018 - nature.com
Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are
becoming major global health emergencies while old threats, such as yellow fever, are re …

Concerning RNA-guided gene drives for the alteration of wild populations

KM Esvelt, AL Smidler, F Catteruccia, GM Church - elife, 2014 - elifesciences.org
Gene drives may be capable of addressing ecological problems by altering entire
populations of wild organisms, but their use has remained largely theoretical due to …

Tissue barriers to arbovirus infection in mosquitoes

AWE Franz, AM Kantor, AL Passarelli, RJ Clem - Viruses, 2015 - mdpi.com
Arthropod-borne viruses (arboviruses) circulate in nature between arthropod vectors and
vertebrate hosts. Arboviruses often cause devastating diseases in vertebrate hosts, but they …

A review of the invasive mosquitoes in Europe: ecology, public health risks, and control options

JM Medlock, KM Hansford, F Schaffner… - Vector-borne and …, 2012 - liebertpub.com
There has been growing interest in Europe in recent years in the establishment and spread
of invasive mosquitoes, notably the incursion of Aedes albopictus through the international …

Genomic mining of prokaryotic repressors for orthogonal logic gates

BC Stanton, AAK Nielsen, A Tamsir, K Clancy… - Nature chemical …, 2014 - nature.com
Genetic circuits perform computational operations based on interactions between freely
diffusing molecules within a cell. When transcription factors are combined to build a circuit …

A horizon scan of global conservation issues for 2014

WJ Sutherland, R Aveling, TM Brooks, M Clout… - Trends in ecology & …, 2014 - cell.com
This paper presents the output of our fifth annual horizon-scanning exercise, which aims to
identify topics that increasingly may affect conservation of biological diversity, but have yet to …

West Nile Virus: biology, transmission, and human infection

TM Colpitts, MJ Conway… - Clinical microbiology …, 2012 - Am Soc Microbiol
SUMMARY West Nile Virus was introduced into the Western Hemisphere during the late
summer of 1999 and has been causing significant and sometimes severe human diseases …

Genetic control of mosquitoes

L Alphey - Annual review of entomology, 2014 - annualreviews.org
Genetics can potentially provide new, species-specific, environmentally friendly methods for
mosquito control. Genetic control strategies aim either to suppress target populations or to …

Beyond insecticides: new thinking on an ancient problem

EA McGraw, SL O'neill - Nature Reviews Microbiology, 2013 - nature.com
Vector-borne disease is one of the greatest contributors to human mortality and morbidity
throughout the tropics. Mosquito-transmitted diseases such as malaria, dengue, yellow fever …