Nuclear PKM2 binds pre-mRNA at folded G-quadruplexes and reveals their gene regulatory role
Nuclear localization of the metabolic enzyme PKM2 is widely observed in various cancer
types. We identify nuclear PKM2 as a non-canonical RNA-binding protein (RBP) that …
types. We identify nuclear PKM2 as a non-canonical RNA-binding protein (RBP) that …
CRISPR/Cas9-mediated high-mobility group A2 knockout inhibits cell proliferation and invasion in papillary thyroid carcinoma cells
S Jin, H Yong, Y Liu, W Bao - Advances in Medical Sciences, 2023 - Elsevier
Purpose Metastasis and recurrence are the prognostic risk factor in patients with thyroid
carcinoma. High-mobility group A2 (HMGA2) protein plays a crucial role in papillary thyroid …
carcinoma. High-mobility group A2 (HMGA2) protein plays a crucial role in papillary thyroid …
CRISPR‐Cas9 Genome Editing and Rapid Selection of Cell Pools
D Stoyko, TO, A Hernandez, P Konstantinidou… - Current …, 2022 - Wiley Online Library
The harnessing of the CRISPR‐Cas9 system allows for quick and inexpensive genome
editing in tissue culture models. Traditional CRISPR‐Cas9 genome editing techniques rely …
editing in tissue culture models. Traditional CRISPR‐Cas9 genome editing techniques rely …