From 2D to 3D cancer cell models—the enigmas of drug delivery research

I Van Zundert, B Fortuni, S Rocha - Nanomaterials, 2020 - mdpi.com
Over the past decades, research has made impressive breakthroughs towards drug delivery
systems, resulting in a wide range of multifunctional engineered nanoparticles with …

To be more precise: the role of intracellular trafficking in development and pattern formation

HM York, J Coyle, S Arumugam - Biochemical Society …, 2020 - portlandpress.com
Living cells interpret a variety of signals in different contexts to elucidate functional
responses. While the understanding of signalling molecules, their respective receptors and …

Real-time multi-angle projection imaging of biological dynamics

BJ Chang, JD Manton, E Sapoznik, T Pohlkamp… - Nature …, 2021 - nature.com
We introduce a cost-effective and easily implementable scan unit that converts any camera-
based microscope with optical sectioning capability into a multi-angle projection imaging …

High-resolution, large imaging volume, and multi-view single objective light-sheet microscopy

B Yang, M Lange, A Millett-Sikking, AC Solak… - BioRxiv, 2020 - biorxiv.org
Light-sheet microscopy has become the preferred method for long-term imaging of large
living samples because of its low photo-invasiveness and good optical sectioning …

Dual-view light-sheet imaging through a tilted glass interface using a deformable mirror

N Vladimirov, F Preusser, J Wisniewski… - Biomedical optics …, 2021 - opg.optica.org
Light-sheet microscopy has become indispensable for imaging developing organisms, and
imaging from multiple directions (views) is essential to improve its spatial resolution. We …

Performance tradeoffs for single-and dual-objective open-top light-sheet microscope designs: a simulation-based analysis

KW Bishop, AK Glaser, JTC Liu - Biomedical Optics Express, 2020 - opg.optica.org
Light-sheet microscopy (LSM) has emerged as a powerful tool for high-speed volumetric
imaging of live model organisms and large optically cleared specimens. When designing …

[HTML][HTML] Combined selective plane illumination microscopy and FRAP maps intranuclear diffusion of NLS-GFP

CM Hobson, ET O'Brien, MR Falvo, R Superfine - Biophysical Journal, 2020 - cell.com
Since its initial development in 1976, fluorescence recovery after photobleaching (FRAP)
has been one of the most popular tools for studying diffusion and protein dynamics in living …

Advanced biological imaging for intracellular micromanipulation: methods and applications

W Gao, L Zhao, Z Jiang, D Sun - Applied Sciences, 2020 - mdpi.com
Intracellular micromanipulation assisted by robotic systems has valuable applications in
biomedical research, such as genetic diagnosis and genome-editing tasks. However …

[PDF][PDF] Optogenetics and light-sheet microscopy

L Maddalena, P Pozzi, NG Ceffa, B Hoeven… - …, 2023 - library.oapen.org
Light-sheet microscopy is a powerful method for imaging small translucent samples in vivo,
owing to its unique combination of fast imaging speeds, large field of view, and low …

Visualization of 3D organoids through the latest advancements in microscopy

M Kumar, R Rauthan, D Chakraborty… - Brain Organoid …, 2022 - Springer
Organoids have enhanced our understanding of in vivo biological processes and the scaling
from cells to tissues to organs. Modern advancements in organoids have achieved …