The influence of biological sex and sex hormones on bile acid synthesis and cholesterol homeostasis
T Phelps, E Snyder, E Rodriguez, H Child… - Biology of sex …, 2019 - Springer
Obesity and elevated serum lipids are associated with a threefold increase in the risk of
developing atherosclerosis, a condition that underlies stroke, myocardial infarction, and …
developing atherosclerosis, a condition that underlies stroke, myocardial infarction, and …
Cholesterol homeostasis: Researching a dialogue between the brain and peripheral tissues
M Gliozzi, V Musolino, F Bosco, M Scicchitano… - Pharmacological …, 2021 - Elsevier
Cholesterol homeostasis is a highly regulated process in human body because of its several
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …
Oxysterols in metabolic syndrome: from bystander molecules to bioactive lipids
O Guillemot-Legris, V Mutemberezi… - Trends in molecular …, 2016 - cell.com
Oxysterols are cholesterol metabolites now considered bona fide bioactive lipids. Recent
studies have identified new receptors for oxysterols involved in immune and inflammatory …
studies have identified new receptors for oxysterols involved in immune and inflammatory …
Localisation of oxysterols at the sub-cellular level and in biological fluids
Oxysterols are oxidized derivatives of cholesterol that are formed enzymatically or via
reactive oxygen species or both. Cholesterol or oxysterols ingested as food are absorbed …
reactive oxygen species or both. Cholesterol or oxysterols ingested as food are absorbed …
Plasma advanced glycation end products and soluble receptor for advanced glycation end products as indicators of sterol content in human carotid atherosclerotic …
RS Pinto, GS Ferreira, GCR Silvestre… - Diabetes and …, 2022 - journals.sagepub.com
Advanced glycation end products (AGEs) are independently related to cardiovascular
disease (CVD) and favor cholesterol and oxysterol accumulation in macrophage foam cells …
disease (CVD) and favor cholesterol and oxysterol accumulation in macrophage foam cells …
[HTML][HTML] Tissue-specific oxysterols as predictors of antidepressant (Escitalopram) treatment response in patients with major depressive disorder
Z Sun, J Yang, J Zhou, J Zhou, L Feng, Y Feng… - … Psychiatry Global Open …, 2023 - Elsevier
Background There is growing evidence that disturbances in cholesterol metabolism may be
involved in major depressive disorder (MDD). However, it is not known if cholesterol …
involved in major depressive disorder (MDD). However, it is not known if cholesterol …
[HTML][HTML] 18F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose …
D Zhang, Z Wang, S Guo, Y Sun, D Zhou, W Li… - Experimental …, 2024 - Elsevier
Total cholesterol (TC) and the cholesterol oxidation product 27-hydroxycholesterol (27-
OHC) are both increased in the elderly. Accumulating evidence has linked 27-OHC to …
OHC) are both increased in the elderly. Accumulating evidence has linked 27-OHC to …
Increased plasma lipids in triple-negative breast cancer and impairment in HDL functionality in advanced stages of tumors
MIBAC Sawada, M de Fátima Mello Santana, M Reis… - Scientific reports, 2023 - nature.com
The association between plasma lipids and breast cancer (BC) has been extensively
explored although results are still conflicting especially regarding the relationship with high …
explored although results are still conflicting especially regarding the relationship with high …
Aerobic exercise training selectively changes oxysterol levels and metabolism reducing cholesterol accumulation in the aorta of dyslipidemic mice
GS Ferreira, PR Pinto, RT Iborra, V Del Bianco… - Frontiers in …, 2017 - frontiersin.org
Background: Oxysterols are bioactive lipids that control cellular cholesterol synthesis,
uptake, and exportation besides mediating inflammation and cytotoxicity that modulate the …
uptake, and exportation besides mediating inflammation and cytotoxicity that modulate the …
Esterification of 4β-hydroxycholesterol and other oxysterols in human plasma occurs independently of LCAT
D Yamamuro, H Yamazaki, J Osuga, K Okada… - Journal of lipid …, 2020 - ASBMB
The acyltransferase LCAT mediates FA esterification of plasma cholesterol. In vitro studies
have shown that LCAT also FA-esterifies several oxysterols, but in vivo evidence is lacking …
have shown that LCAT also FA-esterifies several oxysterols, but in vivo evidence is lacking …