Encapsulated islets for diabetes therapy: history, current progress, and critical issues requiring solution
DW Scharp, P Marchetti - Advanced drug delivery reviews, 2014 - Elsevier
Insulin therapy became a reality in 1921 dramatically saving lives of people with diabetes,
but not protecting them from long-term complications. Clinically successful free islet implants …
but not protecting them from long-term complications. Clinically successful free islet implants …
Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond
M Farina, JF Alexander, U Thekkedath, M Ferrari… - Advanced drug delivery …, 2019 - Elsevier
Cell-based therapy is emerging as a promising strategy for treating a wide range of human
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …
Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques
The transplantation of pancreatic islet cells could restore glycaemic control in patients with
type 1 diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic …
type 1 diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic …
[图书][B] Introduction to nanoscience and nanotechnology
The maturation of nanotechnology has revealed it to be a unique and distinct discipline
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …
[HTML][HTML] Enhancing longevity of immunoisolated pancreatic islet grafts by modifying both the intracapsular and extracapsular environment
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease characterized by
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …
Alginate-based microcapsules for immunoisolation of pancreatic islets
Transplantation of microencapsulated cells is proposed as a therapy for the treatment of a
wide variety of diseases since it allows for transplantation of endocrine cells in the absence …
wide variety of diseases since it allows for transplantation of endocrine cells in the absence …
Cell encapsulation: promise and progress
G Orive, RM Hernández, AR Gascón, R Calafiore… - Nature medicine, 2003 - nature.com
In cell encapsulation, transplanted cells are protected from immune rejection by an artificial,
semipermeable membrane, potentially allowing transplantation (allo-or xenotransplantation) …
semipermeable membrane, potentially allowing transplantation (allo-or xenotransplantation) …
Cell encapsulation via microtechnologies
The encapsulation of living cells in a variety of soft polymers or hydrogels is important,
particularly, for the rehabilitation of functional tissues capable of repairing or replacing …
particularly, for the rehabilitation of functional tissues capable of repairing or replacing …
Microcapsules and microcarriers for in situ cell delivery
In recent years, the use of transplanted living cells pumping out active factors directly at the
site has proven to be an emergent technology. However a recurring impediment to rapid …
site has proven to be an emergent technology. However a recurring impediment to rapid …
Synthetic cells in biomedical applications
Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …
These features include directed localization, sense‐and‐respond behavior, gene …