To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

Mononuclear phagocytes are a widely distributed family of cells contributing to innate and
adaptive immunity. Circulating monocytes and tissue macrophages participate in all stages …

To understand how a protective immune response against SARS-CoV-2 develops over time,
we integrated phenotypic, transcriptional, and repertoire analyses on PBMCs from patients …

Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe
COVID-19. However, the immune signatures associated with immunopathology are poorly …

Type 2 helper T (Th2) cells, a subset of CD4+ T cells, play an important role in the host
defense against pathogens and allergens by producing Th2 cytokines, such as interleukin-4 …

Mucosal barrier alterations may play a role in the pathogenesis of several diseases,
including COVID-19. In this study we evaluate the association between bacterial …

This study examined the roles of microglia and monocytes in myelin destruction in patients
with early multiple sclerosis (MS). Twenty-two cases were studied; the clinical duration was< …

Object The study aimed to utilize the peripheral blood immunological parameters and
resulting individual and combined inflammatory indices [neutrophil/lymphocyte ratio (NLR) …

The Th1/Th2 balance plays a crucial role in the progression of different pathologies and is a
determining factor in the evolution of infectious diseases. This work has aimed to evaluate …

Abstract Coronavirus Disease 2019 (COVID-19) is one of the three lethal coronavirus
outbreaks in the recent two decades and a serious threat to global health all over the world …