Maternal immune activation and neuroinflammation in human neurodevelopmental disorders
Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
Genomics, convergent neuroscience and progress in understanding autism spectrum disorder
More than a hundred genes have been identified that, when disrupted, impart large risk for
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)
HK Hughes, RJ Moreno, P Ashwood - Brain, behavior, and immunity, 2023 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder
characterized by communication and social behavior deficits. The presence of restricted and …
characterized by communication and social behavior deficits. The presence of restricted and …
Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors
including social communication and stereotypies. In addition to genetic risks, the gut …
including social communication and stereotypies. In addition to genetic risks, the gut …
Neurodevelopmental disorders—the history and future of a diagnostic concept
DJ Morris-Rosendahl, MA Crocq - Dialogues in clinical …, 2020 - Taylor & Francis
This article describes the history of the diagnostic class of neurodevelopmental disorders
(NDDs) up to DSM-5. We further analyze how the development of genetics will transform the …
(NDDs) up to DSM-5. We further analyze how the development of genetics will transform the …
[HTML][HTML] Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder
M Sgritta, SW Dooling, SA Buffington, EN Momin… - Neuron, 2019 - cell.com
Currently, there are no medications that effectively treat the core symptoms of Autism
Spectrum Disorder (ASD). We recently found that the bacterial species Lactobacillus (L.) …
Spectrum Disorder (ASD). We recently found that the bacterial species Lactobacillus (L.) …
Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota
Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum
Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors …
Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors …
The contribution of environmental exposure to the etiology of autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous
etiology. While it is widely recognized that genetic and environmental factors and their …
etiology. While it is widely recognized that genetic and environmental factors and their …
Sensory perception in autism
CE Robertson, S Baron-Cohen - Nature Reviews Neuroscience, 2017 - nature.com
Autism is a complex neurodevelopmental condition, and little is known about its
neurobiology. Much of autism research has focused on the social, communication and …
neurobiology. Much of autism research has focused on the social, communication and …
Association of genetic and environmental factors with autism in a 5-country cohort
D Bai, BHK Yip, GC Windham, A Sourander… - JAMA …, 2019 - jamanetwork.com
Importance The origins and development of autism spectrum disorder (ASD) remain
unresolved. No individual-level study has provided estimates of additive genetic, maternal …
unresolved. No individual-level study has provided estimates of additive genetic, maternal …