Cysteine desulfurases utilize a PLP-dependent mechanism to catalyze the first step of sulfur
mobilization in the biosynthesis of sulfur-containing cofactors. Sulfur activation and …

The existence of the thiouridine synthetase, methyltransferase and pseudouridine synthase
(THUMP) domain was originally predicted by a bioinformatic study. Since the prediction of …

Arsenophonus is a widespread insect symbiont with life strategies that vary from parasitism
to obligate mutualism. In insects living exclusively on vertebrate blood, mutualistic …

Sulfuration of uridine 8, in bacterial and archaeal tRNAs, is catalyzed by enzymes formerly
known as ThiI, but renamed here TtuI. Two different classes of TtuI proteins, which possess a …

Phytophagous pentatomid insects can negatively impact agricultural productivity and the
brown marmorated stink bug (Halyomorpha halys) is an emerging invasive pest responsible …

Heterotrophic bacteria and human mitochondria often use sulfide: quinone oxidoreductase
(SQR) and persulfide dioxygenase (PDO) to oxidize sulfide to sulfite and thiosulfate …

Abstract Kissing bugs (Hempitera: Reduviidae) are obligately and exclusively blood feeding
insects. Vertebrate blood is thought to provide insufficient B vitamins to insects, which rely on …

4-Thiouridine (s 4 U) is a conserved modified nucleotide at position 8 of bacterial and
archaeal tRNAs and plays a role in protecting cells from near-UV killing. Escherichia coli …

Sulfur-containing transfer ribonucleic acids (tRNAs) are ubiquitous biomolecules found in all
organisms that possess a variety of functions. For decades, their roles in processes such as …

This paper will describe the biosynthesis of the thiamin thiazole in Bacillus subtilis and
Saccharomyces cerevisiae. The two pathways are quite different: in B. subtilis, the thiazole is …