Multivalent glycocyclopeptides: conjugation methods and biological applications
D Goyard, AMS Ortiz, D Boturyn… - Chemical Society …, 2022 - pubs.rsc.org
Click chemistry was extensively used to decorate synthetic multivalent scaffolds with glycans
to mimic the cell surface glycocalyx and to develop applications in glycosciences …
to mimic the cell surface glycocalyx and to develop applications in glycosciences …
Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: an update for 2015–2016
DJ Harvey - Mass Spectrometry Reviews, 2021 - Wiley Online Library
This review is the ninth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …
The study of multivalent carbohydrate–protein interactions by bio-layer interferometry
E Laigre, D Goyard, C Tiertant, J Dejeu… - Organic & biomolecular …, 2018 - pubs.rsc.org
The study of complex multivalent carbohydrate–protein interactions remains highly
complicated and sometimes rendered impossible due to aggregation problems. In this study …
complicated and sometimes rendered impossible due to aggregation problems. In this study …
Chemical synthesis and immunological evaluation of new generation multivalent anticancer vaccines based on a Tn antigen analogue
C Pifferi, A Ruiz-de-Angulo, D Goyard, C Tiertant… - Chemical …, 2020 - pubs.rsc.org
Tumor associated carbohydrate antigens (TACAs), such as the Tn antigen, have emerged
as key targets for the development of synthetic anticancer vaccines. However, the induction …
as key targets for the development of synthetic anticancer vaccines. However, the induction …
Multivalent glycomimetics with affinity and selectivity toward fucose-binding receptors from emerging pathogens
D Goyard, V Baldoneschi, A Varrot, M Fiore… - Bioconjugate …, 2018 - ACS Publications
Bacterial and fungal pathogens involved in lung infection in cystic fibrosis patients utilize a
particular family of glycan-binding proteins, characterized by the presentation of six fucose …
particular family of glycan-binding proteins, characterized by the presentation of six fucose …
Heterovalent glycodendrimers as epitope carriers for antitumor synthetic vaccines
C Pifferi, B Thomas, D Goyard, N Berthet… - … A European Journal, 2017 - Wiley Online Library
The large majority of TACA‐based (TACA= Tumor‐Associated Carbohydrate Antigens)
antitumor vaccines target only one carbohydrate antigen, thereby often resulting in the …
antitumor vaccines target only one carbohydrate antigen, thereby often resulting in the …
Recent advances in the chemistry of glycoconjugate amphiphiles
L Latxague, A Gaubert, P Barthélémy - Molecules, 2018 - mdpi.com
Glyconanoparticles essentially result from the (covalent or noncovalent) association of
nanometer-scale objects with carbohydrates. Such glyconanoparticles can take many …
nanometer-scale objects with carbohydrates. Such glyconanoparticles can take many …
The advanced synthetic modifications and applications of multifunctional PAMAM dendritic composites
RY Patle, JS Meshram - Reaction Chemistry & Engineering, 2022 - pubs.rsc.org
The profound advances in dendrimer chemistry have led to new horizons in polymer
science. Moreover, this has promisingly uncovered opportunities to develop new versatile …
science. Moreover, this has promisingly uncovered opportunities to develop new versatile …
Heteroglycoclusters With Dual Nanomolar Affinities for the Lectins LecA and LecB From Pseudomonas aeruginosa
D Goyard, B Thomas, E Gillon, A Imberty… - Frontiers in …, 2019 - frontiersin.org
Multivalent structures displaying different instead of similar sugar units, namely
heteroglycoclusters (hGCs), are stimulating the efforts of glycochemists for developing …
heteroglycoclusters (hGCs), are stimulating the efforts of glycochemists for developing …
Synthesis of Mannosylated Glycodendrimers and Evaluation against BC2L‐A Lectin from Burkholderia Cenocepacia
Chronic colonization of lungs by opportunist bacteria is the major cause of mortality for cystic
fibrosis patients. Among these pathogens, Burkholderia cenocepacia is responsible for …
fibrosis patients. Among these pathogens, Burkholderia cenocepacia is responsible for …