Most neurodegenerative disorders are associated with aggregated protein deposits. In the
case of Alzheimer disease (AD), extracellular amyloid-β (Aβ) aggregates and intracellular …

With increasing knowledge of clinical in vivo biomarkers and the pathological intricacies of
Alzheimer's disease (AD), nosology is evolving. Harmonized consensus criteria that …

Background: Although memory impairment is the main symptom of Alzheimer's disease
(AD), language impairment can be an important marker. Relatively few studies of language …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

Objective To characterize in vivo signatures of pathological diagnosis in a large cohort of
patients with primary progressive aphasia (PPA) variants defined by current diagnostic …

Alzheimer's disease is increasingly considered a large-scale network disconnection
syndrome, associated with progressive aggregation of pathological proteins, cortical …

Objective To estimate the prevalence of amyloid positivity, defined by positron emission
tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological …

Cognitive Neuroscience of Language provides an up-to-date, wide-ranging, and
pedagogically practical survey of the most important developments in this exciting field. It …

Fifty-eight autopsies of patients with primary progressive aphasia are reported. Twenty-three
of these were previously described (Mesulam et al., 2008) but had their neuropathological …

The characteristics of early and mild disease in primary progressive aphasia are poorly
understood. This report is based on 25 patients with aphasia quotients> 85%, 13 of whom …