Because of their potent anti-inflammatory properties, corticosteroids have been used for
decades to treat many diseases, including rheumatic diseases. They are frequently used in …

Studies of oral corticosteroid dose and loss of bone mineral density have reported
inconsistent results. In this meta-analysis, we used information from 66 papers on bone …

Objectives: Review the anti-inflammatory, anti-proliferative, and immunosuppressive actions
of corticosteroids. Summarize the monitoring required for corticosteroid therapy. Describe …

Melatonin is a ubiquitous molecule and widely distributed in nature, with functional activity
occurring in unicellular organisms, plants, fungi and animals. In most vertebrates, including …

Background Corticosteroids have been used for the treatment of inflammatory bowel
disease since the late 1940s. Upwards of 80% of patients may respond acutely to treatment …

Objective. This study examined the effects of daily and cumulative oral corticosteroid doses
on the risk of fractures. Methods. Information was obtained from the General Practice …

Abstract purpose: The purpose of this study was to better define the toxicity of low dose (less
than or equal to 15 mg/d prednisone or equivalent) long-term (greater than 1 year) …

The cytokines IL-1 beta and TNF-alpha cause cachexia and hypermetabolism in animal
models, but their role in human inflammation remains controversial. The relationship …

Objective To evaluate predictors of vertebral fractures, including a threshold for bone
mineral density (BMD), in patients receiving oral glucocorticoids (GCs). Methods Data were …

Purpose: To review the clinical picture, pathogenesis, and management of glucocorticoid-
induced osteoporosis. Data Identification: Studies published since 1970 were identified from …