Subgenomic flavivirus RNA as key target for live-attenuated vaccine development
K Doets, GP Pijlman - Journal of Virology, 2024 - Am Soc Microbiol
Live-attenuated flavivirus vaccines confer long-term protection against disease, but the
design of attenuated flaviviruses does not follow a general approach. The non-coding …
design of attenuated flaviviruses does not follow a general approach. The non-coding …
Zika virus dumbbell-1 structure is critical for sfRNA presence and cytopathic effect during infection
ME Graham, C Merrick, BM Akiyama, MJ Szucs… - Mbio, 2023 - Am Soc Microbiol
All flaviviruses contain conserved RNA structures in the 3′ untranslated region (3′ UTR)
that are important for flavivirus RNA replication, translation, and pathogenesis. Flaviviruses …
that are important for flavivirus RNA replication, translation, and pathogenesis. Flaviviruses …
Pan-flavivirus analysis reveals sfRNA-independent, 3′ UTR-biased siRNA production from an insect-specific flavivirus
B Besson, GJ Overheul, MT Wolfinger… - Journal of …, 2024 - journals.asm.org
ABSTRACT RNA interference (RNAi) plays an essential role in mosquito antiviral immunity,
but it is not known whether viral small interfering RNA (siRNA) profiles differ between …
but it is not known whether viral small interfering RNA (siRNA) profiles differ between …
Exosome-mediated viral nucleic acid presentation in a crustacean expounds innate immunity from a novel perspective
Y Gong, H Hu, X Zhao, W Wei, M Zhang… - Journal of …, 2024 - journals.asm.org
As an enduring hot topic in the field of innate immunity, apoptosis is widely considered an
effective approach to eliminate pathogenic microbes and plays a crucial role during host …
effective approach to eliminate pathogenic microbes and plays a crucial role during host …
A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of Flaviviridae
Viruses have developed innovative strategies to exploit the cellular machinery and
overcome the antiviral defenses of the host, often using specifically structured RNA …
overcome the antiviral defenses of the host, often using specifically structured RNA …